Contract Operations Specialist

Definium Therapeutics; Durham (NC); On-site; USD 75,000 - 85,000; Full time

Benefits offered by this job

Health benefits

401(k) plan

Flexible time off

Parental leave

Job summary

Definium Therapeutics, a leading biopharmaceutical company, is seeking a Contracts Operations Specialist to manage contract lifecycle processes and CLM tooling. You will work across legal, procurement, and business teams to ensure accurate data, streamlined workflows, and compliant documentation.

The role supports intake, tracking, execution, and reporting, leveraging Malbek and other tools to drive efficiency.

Qualifications

• Bachelor's degree or equivalent experience.
• Minimum 3 years of experience in contract administration, legal operations, procurement operations, contract lifecycle management, or a related function.
• Experience supporting contract review, execution, records management, or CLM systems. Malbek preferred.
• Strong organizational skills and meticulous attention to detail.
• Ability to manage multiple priorities and deadlines in a fast-paced environment.
• Strong written and verbal communication skills.
• Proficiency with Microsoft Office applications, including Excel, Word, PowerPoint, and Outlook.
• Experience leveraging AI-enabled tools, automation platforms, or legal technology solutions to improve contract lifecycle management, reporting, knowledge management, or operational efficiency.

Responsibilities

• Serve as a primary administrator for the Contract Lifecycle Management (CLM) system.
• Support contract intake, routing, tracking, execution tracking, filing, and signature collection across agreements.
• Maintain contract repositories, metadata, naming conventions, and documentation per requirements.
• Conduct quality control reviews to ensure completeness, consistency, and compliance.
• Support CLM enhancements, user adoption, workflow optimization, and continuous improvement.
• Collaborate with cross-functional stakeholders to improve contracting processes and user experience.
• Generate and maintain contract reports, dashboards, metrics, and management summaries.
• Monitor milestones, renewal dates, notice periods, and key contractual obligations.
• Maintain accurate contract data for operational reporting and analytics.
• Monitor and respond to contract inquiries and maintain templates and playbooks.

Skills

Contract administration

Legal operations

Attention to detail

Communication

Project management

Education

Bachelor's degree

Tools

Malbek CLM

Microsoft Excel

Microsoft Word

PowerPoint

Outlook

Job description

Definium Therapeutics is a late-stage clinical biopharmaceutical company and our mission is to forge a new era of psychiatry by applying scientific rigor to psychedelics, with the goal of developing accessible treatments that unlock healing at scale.

Our leadproductcandidate,lysergidetartrate(ourproprietary orally disintegrating tablet form oflysergide(LSD) D-tartrate),represents a highly differentiated, potential best-in-class opportunity for patients suffering from generalized anxiety, major depressive disorder, and posttraumatic stress disorder. Our early stage pipeline includes DT402, the R-enantiomer of MDMA and is under development to target the core symptoms of autism spectrum disorder (ASD), specifically addressing social communication challenges.

Guided bythe recognitionthat patients deserve more than better, Definium is relentlessly advancing a new generation of therapeutics intended to addresstheunderlying causes of psychiatric and neurological disorders. By turning evidence into impact, Definium aims to change the trajectory of today’s mental health care crisis and enable a healthier future. Headquartered in New York, Definium Therapeutics trades on Nasdaq under the symbol DFTX.

Together we are moving psychiatry forward—beyond better, into a boundless future. Join us!

We are looking for a motivated Contracts Operations Specialist with direct pharmaceutical or biotech experience to join our team. You are highly detail-oriented, process-driven, and passionate about creating efficient and scalable systems. You enjoy working across functions, solving operational challenges, and ensuring contract data and documentation are accurate, complete, and readily accessible. You have a natural interest in process improvement, technology, and automation, and are eager to help optimize the department's contracting operations.

In this role, reporting to the Sr. Contracts Manager, you will support the day-to-day administration of the company's contract lifecycle management processes and systems, including Malbek. You will serve as a key resource for contract intake, tracking, execution support, reporting, data integrity, and continuous process improvement.
Responsibilities:

Contract Lifecycle Management and Administration

• Serve as a primary administrator and subject matter resource for the company's Contract Lifecycle Management (CLM) system
• Support contract intake, routing, tracking, execution tracking, contract filing, and signature collection to facilitate efficient contract processing on a variety of agreements, including confidentiality agreements, vendor agreements, consulting agreements, clinical trial agreements, master services agreements, statements of work and amendments.
• Maintain contract repositories, metadata, records, naming conventions, and supporting documentation in accordance with departmental requirements
• Conduct quality control reviews of contracts and related documentation to ensure completeness, consistency, and compliance with departmental standards.
• Support CLM enhancements, user adoption, workflow optimization, and continuous process improvement initiatives
• Collaborate with cross-functional stakeholders to improve contracting processes and user experience

Reporting and Contract Operations

• Support the generation and maintenance of contract reports, dashboards, metrics, and management summaries.
• Monitor contract milestones, renewal dates, notice periods, and other key contractual obligations.
• Maintain accurate contract data and support operational reporting and analytics for Legal leadership

Legal Department Support

• Monitor and manage the Legal and Contracts shared mailbox and respond to routine contract-related inquiries
• Assist with maintenance of templates, playbooks, training materials, and other contracting resources
• Support onboarding and training related to contracting processes and CLM tools
• Collaborate with attorneys, contract managers, and business stakeholders to address operational contracting needs and support continuous improvement initiatives
• Perform other legal operations and contract administration duties as assigned
• Assist with identifying opportunities to improve contract workflows, reduce manual steps, improve data quality, and enhance user experience

Qualifications

• Bachelor's degree or equivalent experience
• Minimum 3 years of experience in contract administration, legal operations, procurement operations, contract lifecycle management, or a related function
• Experience supporting contract review, execution, records management, or CLM systems. Malbek preffered
• Strong organizational skills and meticulous attention to detail
• Ability to manage multiple priorities and deadlines in a fast-paced environment.
• Strong written and verbal communication skills
• Proficiency with Microsoft Office applications, including Excel, Word, PowerPoint, and Outlook
• Experience leveraging AI-enabled tools, automation platforms, or legal technology solutions to improve contract lifecycle management, reporting, knowledge management, or operational efficiency. Experience working with document management systems, CLM platforms, or enterprise workflow tools
• Willingness to learn, grow, and assume increasing responsibility over time

The starting base pay range for this position is $ 75,000-$85,000. Compensation will be determined based on several factors including, but not limited to, skill set, years of experience, and the employee’s geographic location.

Employees in this role may be entitled to additional compensation, including bonus and equity. Benefits information is listed on our Jobs Page. The Company provides competitive benefits to employees including:

• 100% paid health benefits including Medical, Dental and Vision for you and your dependents
• 401(k) program with company match and vesting after the turn of the first month after your start date
• Flexible time off
• Generous parental leave and some fun fringe perks!