Computational Research Scientist - HIV (Remote)

The Henry M. Jackson Foundation for the Advancement of Military Medicine; Silver Spring (MD); Remote; USD 73,000 - 89,000; Full time

Job summary

An established industry player is seeking a passionate Computational Research Scientist I to join their innovative team. This role focuses on designing and executing computational analyses of transcriptomic and viral sequence data to advance HIV-1 prevention strategies. You will collaborate with a diverse team, develop cutting-edge RNA-seq and genome analysis pipelines, and contribute to impactful publications. This position offers a dynamic work environment where your contributions will directly influence military medicine and public health. If you are driven by research and eager to make a difference, this opportunity is perfect for you.

Benefits

Medical Coverage

Dental Coverage

Vision Coverage

Health Savings Plans

Retirement Plans

Qualifications

• Doctoral degree in Computational Biology or Bioinformatics required.
• 0-2 years of experience in computational genomics or biostatistics.

Responsibilities

• Designs and executes computational analyses of transcriptomic data.
• Develops RNA-seq and genome analysis pipelines for research.

Skills

Computational Genomics

Biostatistics

Programming in R

Scripting (Perl, Python)

C/C++ or Java

Next-Generation Sequencing Analysis

Pipeline Development

Team Collaboration

Communication Skills

Understanding Clinical Data

Education

Doctoral Degree in Computational Biology or Bioinformatics

Tools

HiSeq Analysis Software

Genome Analysis Toolkit (GATK)

Job description

Overview

Join the HJF Team!

HJF is seeking a Computational Research Scientist I who designs and executes computational and statistical analysis of transcriptomic and viral sequence data obtained from HIV-1 infection and vaccine studies to advance HIV-1 prevention and therapeutic applications.

This position will be in support of the Animal Models & Viral Persistence Section of the Military HIV Research Program, led by Dr. Diane Bolton, a senior immunologist and virologist within MHRP. Specific research projects will investigate transcriptional signatures of immune responses and infected cells to inform HIV-1 vaccine and therapeutic strategies against viral infections. This includes assessment of virus-specific T cells and their relationship to antibody responses and virus control in the setting of infection and vaccination. Data sets are generated using cutting-edge immunology and flow cytometry measurements and next-generation gene expression modalities.

The Henry M. Jackson Foundation for the Advancement of Military Medicine (HJF) is a nonprofit organization dedicated to advancing military medicine. We serve military, medical, academic, and government clients by administering, managing, and supporting preeminent scientific programs that benefit members of the armed forces and civilians alike. Since its founding in 1983, HJF has served as a vital link between the military medical community and its federal and private partners.

Note: This site requires that non U.S. Citizens reside in the United States for three of the five recent years.

Responsibilities

• Evaluates, analyzes, and customizes next-generation sequence analysis protocols, e.g. HiSeq Analysis Software, Genome Analysis Toolkit (GATK), open-source software, for a variety of sequencing applications.
• Develops new RNA-seq, Exome seq, genome analysis pipelines and procedures.
• Conducts data-driven and hypothesis-directed genomics research.
• Assists with the report of experimental results for publication in technical and peer-reviewed journals. Contributes and edits data, text, and figures in program publications.
• Presents research in oral communications at internal meetings and at international scientific conferences.
• Collaborates closely with interdisciplinary team members.
• May supervise junior informatics staff.
• May perform other duties and responsibilities as assigned or directed by the supervisor.

Qualifications

Education and Experience

• Doctoral Degree in Computational Biology or Bioinformatics.
• Minimum of 0-2 years experience required.

Required Knowledge, Skills, and Abilities

• Research experience in computational genomics or biostatistics demonstrated through publications; programming ability in R (or other statistical language).
• Scripting language (Perl, Python, or comparable), and (C/C++, Java or comparable language).
• Experience with next-generation sequencing analysis, i.e. alignment, quality assessment, variant detection, statistical inference.
• Experience with pipeline development and implementation on compute clusters.
• Demonstrated ability to work effectively as part of a team in a deadline-driven environment.
• Excellent oral and written communication skills and capable of writing abstracts, manuscripts, and reports.
• Understanding of clinical and immunologic data is a plus.
• Ability to obtain and maintain a T1/Public Trust background check.

Work Environment

• This position will take place primarily in an office setting.

Compensation

• The annual salary range for this position is $73,800 - $89,000. Actual salary will be determined based on experience, education, etc.

Benefits

• HJF offers a comprehensive suite of benefits focused on your health and well-being, from medical, dental, and vision coverage to health savings and retirement plans, and more.

Employment with HJF is contingent upon successful completion of a background check, which may include contacting your professional references, verification of previous employment, education and credentials, a criminal background check, and a department of motor vehicle (DMV) check if applicable.

Equal Opportunity Employer/Protected Veterans/Individuals with Disabilities

The contractor will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant.

Any qualifications to be considered as equivalents, in lieu of stated minimums, require the prior approval of the Chief Human Resources Officer.