Computational Biologist, Microbiome Drug Response

Outpost; Boston, Northern (MA, KY); Hybrid; USD 105,000 - 120,000; Full time

Benefits offered by this job

Equity in company

Comprehensive benefits

Remote-friendly elements

Job summary

Outpost Bio is seeking a Computational Biologist in Boston to turn microbiome data into actionable insights. You will own computational studies and connect experimental measurements to model inputs in a fast-paced environment.

The role involves validating methods, collaborating with wet labs and ML researchers, and contributing to an AI platform that links experiments with analyses. Equity is offered along with comprehensive benefits.

Qualifications

• Requires a doctorate or a master's with ≥3 years industry work and evidence of independent research.
• Hands-on experience analyzing metagenomic or 16S data with understanding of microbial biology and reference databases.
• Strong statistical reasoning including experimental design and handling confounders.
• Proficient in Python and/or R with reproducible analysis code and version control.
• Experience in comparative genomics or pathway annotation is a plus.

Responsibilities

• Run standard analyses on each experimental screen and calibrate to controls.
• Assess datasets before model training; check contamination and batch effects.
• Incorporate new data types into workflows; collaborate with data platform engineers.
• Document assumptions behind computational tools in use.
• Develop and validate methods to analyze 16S and metagenomic data.

Skills

Python

R

metagenomics

16S data analysis

statistical analysis

Education

PhD in relevant field

MS in relevant field + 3+ years industry

Tools

Git

Linux

Nextflow

Snakemake

LC-MS data processing

Job description

Outpost Bio is seeking a Computational Biologist in Boston to turn microbiome data into actionable insights. You will own computational studies and connect experimental measurements to model inputs in a fast-paced environment.

The role involves validating methods, collaborating with wet labs and ML researchers, and contributing to an AI platform that links experiments with analyses. Equity is offered along with comprehensive benefits.