Clinical Variant Scientist - Pathology & Immunology

Washington University in St. Louis; St. Louis (MO); On-site; USD 78,000 - 120,000; Full time

Benefits offered by this job

Vacation time

Transit benefits (Metro U-Pass)

Tuition assistance

Retirement plan

Job summary

Washington University in St. Louis seeks a Clinical Genomics professional to support clinical genomic testing workflows, focusing on variant analysis, curation, and interpretation for germline conditions. You will help develop SOPs and educational materials while ensuring regulatory compliance and quality controls.

You will collaborate with faculty and clinical staff on test development, validation, and translational research, contributing to education initiatives and workflow improvements.

Qualifications

• Master's degree required.
• Ph.D. preferred.
• Relevant experience: 3 years.

Responsibilities

• Analyze, assess, and interpret genetic variation identified via clinical genomic testing workflows.
• Integrate complex information to determine clinical applicability of variants.
• Interpret variants per up-to-date professional guidelines.
• Assess QC metrics related to NGS and variant interpretation.
• Aid clinical staff with variant interpretation.
• Develop tools and processes for genomic testing and reporting.
• Assist with regulatory compliance and SOP maintenance.
• Support translational research initiatives.

Skills

Analytical Thinking

Biology

Genetic Research

Next Generation Sequencing

Data Analysis

Scientific Literature

Team Collaboration

Communication

Education

Master's degree

Ph.D. - Doctor of Philosophy

Tools

Microsoft Office

Clinical Databases

Job description

Position Summary

Location

ST. LOUIS, MO 63108

Scheduled Hours

40

Position Summary

The Clinical Genomics Laboratory is an academic clinical laboratory that provides a range of tests enabling the diagnosis, treatment, and monitoring of inherited and acquired genetic conditions. This position is focused on supporting clinical genomic testing workflows for the diagnosis of suspected constitutional or germline conditions through targeted gene panels and genome-scale sequencing. It will also support clinical education initiatives, and translational research. Focus of the position is on all aspects of genetic variant analysis, curation, and interpretation. Participates in i) evaluation of new tools and platforms; ii) clinical test development and validation; iii) production of standard operating procedures and scholarly/educational materials; and iv) facilitating regulatory compliance.

Job Description

Primary Duties & Responsibilities:

• Analyze, assess, and interpret genetic variation identified via clinical genomic testing workflows (targeted and comprehensive genomic testing).
• Analyze and integrate complex information from multiple sources to determine applicability of identified genetic variation to clinical care.
• Interpret genetic variation in accordance with up-to-date professional society guidelines.
• Assess quality control metrics as they relate to next generation sequencing and variant interpretation.
• Aid clinical staff, residents, and fellows with conducting variant interpretation.
• Develop, implement, and evaluate information, tools, and processes to assist clinical faculty/staff with clinical genomic testing, variant analysis/interpretation, and reporting.
• Work with clinical genomics test development, improvement, optimization, validation, and assurance of regulatory compliance.
• Aid with maintaining standard operating procedures for clinical genomic workflows.
• Support clinical and research faculty/staff with translational research projects.

Working Conditions:

This position will follow a Sunday-Thursday work week. It is preferred that the incumbent will work on-site at the Washington University School of Medicine; however, individuals who wish to work off-site, remotely, will certainly be considered.

The above statements are intended to describe the general nature and level of work performed by people assigned to this classification. They are not intended to be construed as an exhaustive list of all job duties performed by the personnel so classified. Management reserves the right to revise or amend duties at any time.

Education

Required Qualifications

Master's degree

Certifications/Professional Licenses

No specific certification/professional license is required for this position.

Work Experience

Relevant Experience (3 Years)

Skills

Not Applicable

Driver's License

A driver's license is not required for this position.

More About This Job

WashU seeks highly motivated individuals who are able to perform duties in a manner consistent with our core mission and guiding principles.

Education

Preferred Qualifications

Ph.D. - Doctor of Philosophy

Certifications/Professional Licenses

No additional certification/professional licenses unless stated elsewhere in the job posting.

Work Experience

No additional work experience unless stated elsewhere in the job posting.

Skills

Analytical Processes, Analytical Thinking, Biology, Clinical Databases, Clinical Laboratory Operations, Communication, Data Security, Deadline Management, Detail-Oriented, Genetic Research, Group Problem Solving, Integration Management, Microsoft Office, Next Generation Sequencing (NGS), Next Generation Sequencing Data Analysis, Organizing, Prioritization, Process Optimization, Scientific Literature, Stress Management, Team Collaboration, Working Independently

Grade

C14

Salary Range

$77,700.00 - $120,400.00 / Annually

The salary range reflects base salaries paid for positions in a given job grade across the University. Individual rates within the range will be determined by factors including one's qualifications and performance, equity with others in the department, market rates for positions within the same grade and department budget.

Questions

For frequently asked questions about the application process, please refer to our External Applicant FAQ.

Accommodation

If you are unable to use our online application system and would like an accommodation, please email [e-mail] or call the dedicated accommodation inquiry number at 314-935-1149 and leave a voicemail with the nature of your request.

All qualified individuals must be able to perform the essential functions of the position satisfactorily and, if requested, reasonable accommodations will be made to enable employees with disabilities to perform the essential functions of their job, absent undue hardship.

Pre-Employment Screening

All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.

Benefits Statement

Personal

• Up to 22 days of vacation, 10 recognized holidays, and sick time.
• Competitive health insurance packages with priority appointments and lower copays/coinsurance.
• Take advantage of our free Metro transit U-Pass for eligible employees.
• WashU provides eligible employees with a defined contribution (403(b)) Retirement Savings Plan, which combines employee contributions and university contributions starting at 7%.

Wellness

• Wellness challenges, annual health screenings, mental health resources, mindfulness programs and courses, employee assistance program (EAP), financial resources, access to dietitians, and more!

Family

• We offer 4 weeks of caregiver leave to bond with your new child. Family care resources are also available for your continued childcare needs. Need adult care? We’ve got you covered.
• WashU covers the cost of tuition for you and your family, including dependent undergraduate-level college tuition up to 100% at WashU and 40% elsewhere after seven years with us.

For policies, detailed benefits, and eligibility, please visit: https://hr.wustl.edu/benefits/

EEO Statement

Washington University in St. Louis is committed to the principles and practices of equal employment opportunity. It is the University’s policy to provide equal opportunity and access to persons in all job titles without regard to race, ethnicity, color, national origin, citizenship (where prohibited by federal law), age, religion, sex, sexual orientation, gender identity or expression, disability, protected veteran status, or genetic information.