Clinical Trial Manager (CTM)

Nurix Therapeutics; Brisbane (CA); On-site; USD 158,000 - 168,000; Full time

Job summary

Nurix Therapeutics is seeking a Clinical Operations Lead to own assigned trials from start-up through close-out, with the autonomy to make daily calls and support from an experienced team.

You will manage day-to-day CRO/vendor relationships, build strong site investigator partnerships, monitor enrollment, and oversee budgets, forecasting, and data deliverables. The role involves contributing to regulatory audits and collaborating with cross-functional teams.

Qualifications

• Fluently capable of managing trials from start-up to close-out.
• Experience leading CRO/vendor relationships and study teams.
• Knowledge of FDA/EMA/ICH/GCP guidelines and regulations.
• Strong analytical, problem-solving and communication skills.
• Ability to manage time, information gaps, and shifting priorities.

Responsibilities

• Own all operational aspects of assigned clinical trials from startup to close-out.
• Lead study team, vendors, monitors, and clinical sites throughout the lifecycle.
• Manage day-to-day CRO/vendor relationships to meet budgets, timelines, and protocol.
• Build relationships with site investigators and study coordinators.
• Track trial progress and update stakeholders on status.
• Monitor enrollment and address recruitment challenges as they arise.
• Manage study budget, forecasting, accruals, and vendor payments.
• Coordinate with Data Management on CRF content and data deliverables.
• Draft protocols, informed consents, CRFs, monitoring plans, and reports.
• Prepare for regulatory audits and inspections; flag risks early and propose solutions.
• Represent Clinical Operations at project team meetings.

Skills

Trial management

Vendor management

Regulatory knowledge

Analytical skills

Communication

Time management

Organization

Fast-paced environment

Education

BS in biological sciences

Job description

You’ll take full ownership of your assigned trial(s) — from protocol development to close‑out — with the autonomy to make daily calls and the support of an experienced team when it counts.

Position Description

This individual is responsible for the management of assigned clinical trial(s), leading the study team, vendors, clinical monitors, and clinical sites throughout the trial lifecycle.

The Opportunity

• Own all operational aspects of your assigned clinical trial(s)
• Manage day-to-day CRO/vendor relationships to keep deliverables on budget, timeline, and protocol
• Build strong working relationships with site investigators and study coordinators
• Track trial progress and keep stakeholders updated on status
• Monitor enrollment and address recruitment challenges as they arise
• Manage study budget, forecasting, accruals, and vendor payments for your trial(s)
• Partner with Data Management on CRF content, completion guidelines, and data deliverables
• Draft and coordinate review of protocols, informed consents, CRFs, monitoring plans, and study reports
• Prepare for and support regulatory agency audits and inspections
• Flag risks early and recommend solutions before they become problems
• Represent Clinical Operations at project team meetings

What You’ll Bring

• S./B.A. in biological sciences with 5+ years of relevant industry experience
• Ability to travel as required for the program (25%)
• Working knowledge of FDA, EMA, ICH, and GCP regulations and guidelines
• Experience managing trials independently from start-up through close‑out
• Comfortable leading day-to-day CRO/vendor relationships
• Strong analytical and problem‑solving skills
• Clear, confident communicator who can create direction for a study team
• Ability to manage time demands, incomplete information, and shifting priorities
• Highly organized, able to multi‑task and prioritize independently
• Thrives in a fast‑paced, small‑company environment

Salary Range:

$157,700 - $168,200 annually

The posted range applies to roles based in the San Francisco Bay Area and reflects local market conditions. Where an offer lands within that range depends on the candidate’s relevant experience, technical expertise, and how their background aligns with the role’s requirements.

Location:

Onsite - Brisbane, CA

Fit with Nurix Culture and Values

• Strong team orientation; highly collaborative
• Solutions and results-oriented focus
• Hands‑on approach; resourceful and open to diverse points of view

About Nurix Therapeutics

Nurix Therapeutics is a clinical stage biopharmaceutical company focused on the discovery, development, and commercialization of targeted protein degradation medicines, the next frontier in innovative drug design aimed at improving treatment options for patients with cancer and inflammatory diseases. Powered by a fully AI-integrated discovery engine capable of tackling any protein class, and coupled with unparalleled ligase expertise, Nurix's dedicated team has built a formidable advantage in translating the science of targeted protein degradation into clinical advancements. Nurix aims to establish degrader-based treatments at the forefront of patient care, writing medicine’s next chapter with a new script to outmatch disease.