Clinical Trial Manager

precisionmedicinegroup; United States; Remote; USD 130,000 - 190,000; Full time

Benefits offered by this job

Remote work

International travel

Job summary

Precisionmedicinegroup is seeking a seasoned Clinical Lead to manage oncology studies across multiple countries. You will coordinate site selection, activation, enrollment, monitoring, data cleaning, and close-out while ensuring quality, scope, and timelines.

You will mentor CRAs and collaborate with cross-functional teams to maintain regulatory documentation, study oversight, and effective communication with sponsors. International travel will be involved.

Qualifications

• Bachelor’s degree or equivalent in science or health-related field, with oncology experience.
• Significant oncology trial-management experience in a CRO, pharmaceutical, or biotechnology setting.
• Experience leading clinical study activities across multiple countries.
• Working knowledge of ICH-GCP and regulatory guidance.
• Strong English communication and organizational skills; able to manage shifting priorities.
• Proficiency with CTMS, eTMF, EDC, IXRS; travel domestically and internationally.

Responsibilities

• Direct clinical operations across assigned studies and ensure required trial deliverables are completed.
• Coordinate site selection, activation, enrollment, site support, monitoring plans, data cleaning, and study close-out.
• Work with cross-functional colleagues to maintain regulatory documentation, communication, and appropriate study oversight.
• Lead and mentor CRAs, supporting site relationships and oversight of monitoring, regulatory matters, investigational product, payments, and correspondence.
• Identify schedule and delivery risks early and develop practical response plans with study teams and sponsors.
• Maintain focus on study priorities through clear communication and effective collaboration with internal and external partners.

Skills

Leadership

Clinical operations

Communication

Project management

Oncology experience

Education

Bachelor's degree in science/health

Tools

CTMS

eTMF

EDC

IXRS

Job description

Role overview

Manage the clinical delivery of oncology studies across multiple countries, serving as the central coordinator for study teams and leading clinical research associates. You will oversee trial execution from site selection and start-up through enrollment, monitoring, data cleaning, and close-out, with accountability for quality, scope, and timelines.

Responsibilities

• Direct clinical operations across assigned studies and ensure required trial deliverables are completed.
• Coordinate site selection, activation, enrollment, site support, monitoring plans, data cleaning, and study close-out.
• Work with cross-functional colleagues to maintain regulatory documentation, communication, and appropriate study oversight.
• Lead and mentor CRAs, supporting their site relationships and oversight of monitoring, regulatory matters, investigational product, payments, and correspondence.
• Identify schedule and delivery risks early and develop practical response plans with study teams and sponsors.
• Maintain focus on study priorities through clear communication and effective collaboration with internal and external partners.

Requirements

• Bachelor’s degree or equivalent education and experience in a science or health-related field, with oncology experience.
• Significant oncology trial-management experience and a dedicated clinical-lead background in a CRO, pharmaceutical, or biotechnology setting.
• Experience leading clinical study activities across multiple countries.
• Working knowledge of ICH-GCP, clinical development, and applicable regulatory guidance.
• Effective English communication, strong organization, and ability to manage shifting priorities while maintaining quality.
• Proficiency with common office and project tools and clinical systems such as CTMS, eTMF, EDC, or IXRS; availability for domestic and international travel, including overnight stays.

Nice to have

• Experience with CAR-T studies or radiopharmaceuticals.

Benefits and work setup

• Remote work is available from Hungary, Poland, Romania, Serbia, or Slovakia. The role includes travel within and outside the country.