Clinical Research Nurse-Lymphoma

aa067; Duarte (CA); On-site; USD 110,000 - 140,000; Full time

Job summary

City of Hope seeks a compassionate Clinical Research Nurse in California to guide patients through oncology clinical trials. You will collaborate with physicians, CRA, pharmacists, and coordinators to manage eligibility, monitoring, and protocol-specific activities while maintaining regulatory compliance.

Ideal candidates hold a BSN and a current California RN license, with 2+ years in oncology or clinical research.

Qualifications

• BSN required and California RN license must be current.
• 2+ years of experience in oncology or clinical research settings.
• Demonstrated knowledge of IRB processes and regulatory requirements.

Responsibilities

• Manage clinical trial processes and patient eligibility with investigators.
• Monitor patient conditions, document changes, and ensure protocol adherence.
• Coordinate cross-functional care across outpatient, inpatient, and home settings.
• Triage calls, educate patients and families, and support informed consent procedures.
• Collaborate with physicians, NPs, PAs, pharmacists, and research teams.
• Ensure complete and compliant trial documentation to avoid deviations.

Skills

Clinical research

Oncology

IRB compliance

Patient education

Team collaboration

Education

BSN

California RN License

Tools

AHA BLS Certification

Job description

Join the transformative team at City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. City of Hope’s growing national system includes its Los Angeles campus, a network of clinical care locations across Southern California, a new cancer center in Orange County, California, and treatment facilities in Atlanta, Chicago and Phoenix. Our dedicated and compassionate employees are driven by a common mission: To deliver the cures of tomorrow to the people who need them today.

Are you a compassionate and detail-oriented Registered Nurse passionate about advancing healthcare? Join our team as a Clinical Research Nurse, where you’ll play a vital role in guiding patients through innovative clinical trials while collaborating with a multidisciplinary team of physicians, Clinical Research Associates (CRA), pharmacists, and coordinators.

This is a unique opportunity to blend clinical expertise with research excellence—helping bring groundbreaking treatments to life while delivering exceptional patient-centered care.

What You’ll Do

Clinical Trial Patient Management

• Partner with investigators to determine patient eligibility and ensure accurate documentation of clinical trial criteria
• Assess, monitor, and document patient conditions, treatment responses, and changes in health status in accordance with IRB protocols
• Coordinate care across the continuum (outpatient, inpatient, and home settings)
• Triage patient calls and provide proactive communication and support to patients and families
• Collaborate closely with physicians, nurse practitioners (NPs), physician assistants (PAs), pharmacists, and research teams
• Plan and execute protocol-specific activities including randomization, assessments, treatments, and follow-ups
• Ensure all clinical trial documentation is complete, accurate, and compliant to avoid protocol deviations
• Support and monitor patient adherence to study protocols

Patient & Family Education

• Educate patients and families on clinical trial treatments, procedures, and follow-up care
• Provide ongoing support to ensure understanding and adherence to treatment plans

Informed Consent & Compliance

• Ensure informed consent processes meet all regulatory requirements (IRB, FDA, institutional, and sponsor guidelines)
• Participate in patient education during consent and elevate concerns to the Principal Investigator
• Maintain timely and accurate documentation of consent forms

Protocol Oversight & Collaboration

• Assist with study initiation, monitoring visits, and audits
• Collaborate with research pharmacy and investigators to develop and implement protocol-specific orders
• Promote adherence to clinical trial protocols and regulatory standards
• Coordinate scheduling of patient visits, testing, and follow-ups
• Educate nursing staff on protocol requirements and safe medication administration

Additional Responsibilities

• Deliver patient-centered care in alignment with organizational policies and the California Nurse Practice Act
• Maintain a high standard of professionalism, teamwork, and organization
• Stay current with clinical research regulations, standards, and best practices
• Serve as a mentor or preceptor for new staff and nursing students
• Collaborate with internal teams and external partners including physicians, sponsors, and community resources
• Full time 4/10's

Your qualifications should include:

• BSN
• 2 or more years of experience in oncology. clinical research, research, ICU, other intensive care setting, pediatrics, case management or nurse navigation.
• Human subjects protection training (can be completed after hire)

Required Certification/Licensure:

• Current California RN License
• American Heart Association BLS Certification

City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.

City of Hope is an equal opportunity employer.

To learn more about our Comprehensive Benefits, please CLICK HERE.