Clinical Research Nurse III

University of Minnesota; Saint Paul (MN); On-site; USD 85,000 - 110,000; Full time

Benefits offered by this job

Competitive wages

Paid holidays and generous time off

Tuition Benefit Program and continuous

Employee wellbeing program

Excellent retirement plans

Job summary

The University of Minnesota’s Masonic Cancer Center is seeking a nurse to coordinate multiple oncology/hematology clinical trials. You will manage start-up to closeout, assist with patient enrollment, and educate staff and families on protocols, potential side effects, and safety measures.

Required BSN and Minnesota RN licensure with 4+ years of nursing experience (or 8 years education/experience); oncology or clinical research experience strongly preferred. EPIC/Oncore experience is a plus.

Qualifications

• BS degree in Nursing and MN nursing license in Minnesota.
• At least 4 years of professional nursing experience or an advanced degree with 2 years of relevant experience, or 8 years combined education/experience.
• Pediatric or adult oncology/hematology clinical experience or clinical research experience.
• Experience with Word, Outlook, and web-based systems for tracking activities and information.
• Ability to work independently, make decisions, problem solve and prioritize multiple studies.

Responsibilities

• Coordinate all aspects of multiple oncology/hematology trials.
• Administer medications and treatments per protocol.
• Assist with start-up, patient recruitment, consent, enrollment, and registrations.
• Provide education to staff, patients, and families about protocols and side effects.
• Ensure data collection and entry from charts, EMR, and communications.
• Support regulatory documentation and adverse event reporting.

Skills

Oncology/hematology clinical trials

Independent work

Communication skills

Word/Outlook/web-based systems

Scheduling flexibility

Education

BSN or higher

Tools

EPIC

Oncore

Job description

Location: Twin Cities

Full/Part Time: Full-Time

About the Job

Coordinate all aspects of multiple oncology and/or hematology clinical trials for solid tumor malignancies. Clinical trials include Phase I-II trials under locally held INDs, as well as Phase II/III industry sponsored trials. This requires multidisciplinary skills directed towards clinical patient management and safety, protocol administration, providing education and training to research staff, clinical staff, medical providers, patients and their families.

Incumbent at this level knows fundamental concepts, practices and procedures. Identifies and resolves readily identifiable problems. Utilizes the nursing process and standards to perform protocol‑specific procedures, prevent or manage research subjects' participation in all clinical research settings.

Administers medications and treatments, as defined by study protocol. Conducts, coordinates and serves as a resource for various aspects of clinical trials from start‑up to closeout according to study protocols.

• Contributes to study start‑up activities, including site initiation visits, document template creation, study staff training, and clinical in‑services.
• Patient recruitment, screening, consent, enrollment and necessary registrations.
• Provides education to staff, subjects and families about protocols, treatment, possible side effects and complications.
• Performs study data collection and entry; collect enrollment and treatment data, using charts, correspondence, electronic medical records and personal communications with other healthcare workers.
• Assists research team with routine quality control checks.
• Assist with study close‑out activities as directed.
• Completes and submits required documentation to regulatory agencies. Identifies and assesses defined adverse events and reports to appropriate parties. May be done in collaboration with a Regulatory Specialist.
• Participates in production of research publications or presentation of research data.

*These factors are used to determine the complexity of a clinical trial: Level of Disease, Level of Acuity, Independence Level of Thinking/Knowledge Level, Level of Supervision.

Qualifications

All required qualifications must be documented on application materials.

REQUIRED:

• BS degree in Nursing, current licensure to practice as a Registered Nurse in the State of Minnesota, AND at least 4 years of professional nursing experience or advanced degree plus at least two years of relevant experience, or a combination of education and relevant work experience to equal at least eight years.
• Must have pediatric or adult oncology/hematology clinical experience or clinical research experience.
• Experience with Word, Outlook, and web-based systems for tracking activities, calendaring, and retrieving/updating information.
• Demonstrated/documented ability to work independently, make decisions, problem solve and prioritize the simultaneous management of multiple clinical studies.
• Possess excellent communication skills; verbal and written.
• Flexibility with work schedule to accommodate subject visits.

*Proof of non‑active tuberculosis and immunization for or resistance to measles, mumps, rubella, Hepatitis B, pertussis and influenza are required.

PREFERRED:

• Experience with pediatric or adult oncology/hematology clinical trials.
• Experience with EPIC.
• Familiarity with the University of Minnesota, University of Minnesota Medical Center Fairview hospital and clinics.
• Phlebotomy skills.
• Ability to integrate clinical care with clinical research to meet the needs of the patient.
• Experience with Oncore or equivalent clinical trials management system.

About the Department

The Masonic Cancer Center (MCC) is an NCI‑designated Comprehensive Cancer Center dedicated to cancer research, education, and patient care for the citizens of Minnesota and the surrounding region. Since the time of the first award in 1997, there has been consistent growth of the membership and research base, enabling our center to further advance our knowledge and enhance care for our catchment area. We are driven to be the choice academic healthcare environment for patients, clinicians, scientists and students who seek exceptional, compassionate, precision cancer therapy; innovative clinical trials and prevention programs; cutting‑edge research opportunities; and outstanding advanced education.

Pay and Benefits

Pay Range: $85,000 - $110,000; depending on education/qualifications/experience

Time Appointment: 100% Appointment

Position Type: Civil‑Service & Non‑Faculty Labor Represented Staff

Please visit the Office of Human Resources website for more information regarding benefit eligibility.

The University offers a comprehensive benefits package that includes:

• Competitive wages, paid holidays, and generous time off
• Continuous learning opportunities through professional training and degree‑seeking programs supported by the Regents Tuition Benefit Program
• Low‑cost medical, dental, and pharmacy plans
• Healthcare and dependent care flexible spending accounts
• University HSA contributions
• Disability and employer‑paid life insurance
• Employee wellbeing program
• Excellent retirement plans with employer contribution
• Public Service Loan Forgiveness (PSLF) opportunity
• Financial counseling services
• Employee Assistance Program with eight sessions of counseling at no cost
• Employee Transit Pass with free or reduced rates in the Twin Cities metro area

While our salary ranges provide a framework, it is important to note that most of the time, the initial pay may not reach the maximum of the range. This approach ensures that compensation reflects the value and unique contributions of each candidate while maintaining equity within our organization. As part of our commitment to fair and equitable compensation, please be aware that the salary offered to incoming candidates will be based on their individual credentials and experience.

Diversity

The University recognizes and values the importance of diversity and inclusion in enriching the employment experience of its employees and in supporting the academic mission. The University is committed to attracting and retaining employees with varying identities and backgrounds.

The University of Minnesota provides equal access to and opportunity in its programs, facilities, and employment without regard to race, color, creed, religion, national origin, gender, age, marital status, disability, public assistance status, veteran status, sexual orientation, gender identity, or gender expression. To learn more about diversity at the U: http://diversity.umn.edu

Employment Requirements

Any offer of employment is contingent upon the successful completion of a background check. Our presumption is that prospective employees are eligible to work here. Criminal convictions do not automatically disqualify finalists from employment.

About University of Minnesota

The University of Minnesota, Twin Cities (UMTC)

The University of Minnesota, Twin Cities (UMTC), is among the largest public research universities in the country, offering undergraduate, graduate, and professional students a multitude of opportunities for study and research. Located at the heart of one of the nation's most vibrant, diverse metropolitan communities, students on the campuses in Minneapolis and St. Paul benefit from extensive partnerships with world-renowned health centers, international corporations, government agencies, and arts, nonprofit, and public service organizations.

At the University of Minnesota, we are proud to be recognized by Forbes as a Best Employer for Company Culture (2026), Best Employer for Women (2023, 2025, 2026), and Best Employer by State (2022-2026). In 2026, we also received Culture Excellence & Industry Awards recognition for employee appreciation and work‑life flexibility.