Clinical Research Associate II / Sr CRA - Full Service - ONC + Gen Med (Home-Based in Central US)

Syneos Health, Inc.; South Dakota; Remote; USD 70,000 - 127,000; Full time

Job summary

A leading biopharmaceutical solutions organization is seeking a Clinical Research Associate II / Sr CRA to ensure compliance in clinical studies through on-site and remote monitoring. Responsibilities include developing tools to maintain quality, managing project components, and collaborating with cross-functional teams. Candidates should have a Bachelor's degree, 2-4 years in clinical monitoring, and strong knowledge of GCP. Benefits include health coverage, 401k matching, and flexible PTO.

Benefits

Health benefits (Medical, Dental, Vision)

Company match 401k

Flexible paid time off (PTO)

Qualifications

• Minimum of 2-4 years of experience in clinical research monitoring.
• Ability to work independently and manage multiple priorities.

Responsibilities

• Conduct on-site and remote monitoring of clinical research studies.
• Develop and implement tools and procedures for quality monitoring.
• Ensure accurate and timely documentation of monitoring activities.

Skills

Strong knowledge of Good Clinical Practice (GCP)

Excellent communication skills

Problem-solving abilities

Attention to detail

Time management skills

Education

Bachelor's degree in a related field

Certified Clinical Research Associate (CCRA) or equivalent certification

Tools

Clinical trial management systems

Microsoft Office Suite

Job description

Overview

Clinical Research Associate II / Sr CRA - Full Service - ONC + Gen Med (Home-Based in Central US)
Updated: September 22, 2025
Location: USA-SD-Remote
Job ID: 25101627

Syneos Health is a leading fully integrated biopharmaceutical solutions organization built to accelerate customer success. We translate unique clinical, medical affairs and commercial insights into outcomes to address modern market realities. Our Clinical Development model centers on the patient and the customer to simplify and streamline work, whether in a Functional Service Provider partnership or a Full-Service environment.

Discover what our 29,000 employees across 110 countries already know: WORK HERE MATTERS EVERYWHERE

Job Responsibilities

• Conduct on-site and remote monitoring of clinical research studies to ensure compliance with clinical practices, including reviewing study protocols, informed consent forms, and case report forms.
• Develop and implement tools, procedures, and processes to ensure quality monitoring (e.g., monitoring plans, checklists, templates).
• Contribute to the design, implementation, and delivery of processes, programs, and policies, including SOPs and training materials.
• Manage defined components of projects or processes within the area of responsibility (e.g., coordinating site visits, tracking study progress, resolving issues).
• Ensure accurate and timely documentation of monitoring activities and findings (monitoring reports, follow-up letters, action plans).
• Collaborate with cross-functional teams to support clinical trial operations, including investigators, site staff, and other stakeholders to ensure smooth study conduct.

Qualifications

• Bachelor's degree in a related field or equivalent experience.
• Minimum of 2-4 years of experience in clinical research monitoring.
• Strong knowledge of Good Clinical Practice (GCP) guidelines and regulatory requirements.
• Excellent communication and interpersonal skills; ability to work independently and manage multiple priorities.
• Proficiency in using clinical trial management systems and other relevant software.

Certifications

• Certified Clinical Research Associate (CCRA) or equivalent certification preferred.

Necessary Skills

• Attention to detail and strong analytical skills.
• Problem-solving abilities and critical thinking.
• Ability to work effectively in a team environment.
• Strong organizational and time management skills.
• Proficiency in Microsoft Office Suite.

Benefits and Compensation

The benefits for this position may include a company car or car allowance, health benefits (Medical, Dental, Vision), company match 401k, eligibility to participate in Employee Stock Purchase Plan, eligibility to earn commissions/bonus based on company and individual performance, and flexible paid time off (PTO) and sick time. Paid sick time eligibility varies by location. Syneos complies with applicable paid sick time requirements.

Salary Range: $70,100.00 - $126,100.00

The base salary range represents the anticipated low and high of the Syneos Health range for this position. Actual salary will vary based on qualifications, skills, and proficiency for the role.

Get to know Syneos Health

Over the past 5 years, we have worked with 94% of Novel FDA Approved Drugs, 95% of EMA Authorized Products and over 200 studies across 73,000 sites and 675,000+ trial patients.

No matter your role, you’ll take the initiative and challenge the status quo in a highly competitive environment. Learn more about Syneos Health.

Website: http://www.syneoshealth.com

Additional Information

Tasks, duties, and responsibilities are not exhaustive. The Company may assign other tasks, duties, and responsibilities at its sole discretion. Equal opportunity employer statement and accommodations information are provided below.

Syneos Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, marital status, ethnicity, national origin, sex, gender, gender identity, sexual orientation, protected veteran status, disability or any other legally protected status. If you require reasonable accommodation to complete any part of the application process, please contact [e-mail].

Summary

Roles within Clinical Monitoring/CRA job family at the P21 level are responsible for ensuring that clinical research studies are conducted in accordance with widely accepted clinical practices, including conducting on-site and remote monitoring, developing tools and processes, and managing defined project components. The majority of the time is spent contributing to the design, implementation, or delivery of processes, programs, and policies.

Contact: Syneos Health