Clinical Research Associate II

Piper Companies; United States; Remote; USD 100,000 - 130,000; Full time

Benefits offered by this job

Medical, Dental, Vision

401(k)

Job summary

Piper Companies is seeking a Clinical Research Associate II for a remote permanent role with extensive field responsibilities across the United States.

The CRA II will monitor cardiovascular, CNS, and metabolic studies, collaborate with investigative sites, and ensure high-quality trial execution while maintaining regulatory compliance and efficient data capture. Travel will be 60-75% nationwide.

Qualifications

• 1-4 years of onsite clinical monitoring experience.
• Experience supporting cardiovascular, CNS, diabetes, or metabolic trials.
• Strong knowledge of GCP and ICH guidelines and FDA regulations.
• Proficiency with CTMS and EDC systems.
• Bachelor's degree in life sciences or nursing; Spanish fluency preferred for FL/PR.

Responsibilities

• Perform routine and close-out monitoring visits to ensure trials are conducted in alignment with GCP, ICH, and applicable regulations.
• Serve as the primary contact for assigned research sites, fostering strong relationships and ongoing communication.
• Review site data, source documentation, and regulatory files to confirm accuracy, completeness, and protocol adherence.
• Provide guidance and training to site staff on protocol requirements, study procedures, and compliance expectations.
• Identify, document, and elevate quality or compliance concerns while supporting resolution efforts.

Skills

Onsite monitoring

Regulatory compliance

Site relationship management

GCP/ICH knowledge

Education

Bachelor's degree in life sciences

Tools

CTMS

EDC

Job description

Piper Companies is seeking a Clinical Research Associate II to join a global organization within the clinical research and life sciences industry for a remote permanent role with a 60-75% travel across the United States. This CRA II will support cardiovascular, CNS, and metabolic studies while partnering closely with investigative sites to ensure high-quality trial execution.

Responsibilities of the Clinical Research Associate II include:

• Perform routine and close-out monitoring visits to ensure studies are conducted in alignment with GCP, ICH, and applicable regulations.
• Serve as the primary point of contact for assigned research sites, fostering strong relationships and ongoing communication.
• Review site data, source documentation, and regulatory files to confirm accuracy, completeness, and protocol adherence.
• Provide guidance and training to site staff on protocol requirements, study procedures, and compliance expectations.
• Identify, document, and elevate quality or compliance concerns while supporting resolution efforts.

Qualifications for the Clinical Research Associate II include:

• 1-4 years of onsite clinical monitoring experience, aligned to CRA II or Senior CRA I level.
• Experience supporting clinical trials within cardiovascular, CNS, diabetes, or metabolic indications.
• Strong working knowledge of GCP, ICH guidelines, and FDA regulatory requirements.
• Proficiency with CTMS, EDC systems, and standard clinical trial documentation.
• Bachelor's degree in life sciences, nursing, or a related discipline; Spanish fluency is highly preferred for candidates based in Florida or Puerto Rico.

Compensation for the Clinical Research Associate II:

Salary Range: $100,000-$130,000/year (USD)

Comprehensive Benefits: Medical, Dental, Vision, sick leave if required by law, and 401(k)

This job opens for applications on 10/30/26. Applications for this job will be accepted for at least 30 days from the posting date.

Keywords: clinical research, clinical trials, CRA, GCP, ICH, regulatory compliance, site monitoring, clinical monitoring, CTMS, EDC, cardiovascular studies, CNS trials, diabetes research, GLP-1, site management, FDA regulations, clinical operations, documentation, quality assurance, protocol compliance, investigator sites, patient safety, clinical development.