Senior Clinical Research Associate - 177466

Piper Companies; United States; Remote; USD 155,000 - 175,000; Full time

Job summary

Piper Companies is seeking a Senior Clinical Research Associate (CRA) to support oncology trials for a well-established organization. The role is a 6-month remote contract where the Senior CRA will act as the primary CRA on assigned Phase II and III studies, with a mix of onsite and remote monitoring and extensive interaction with sites.

The role requires 2+ years of oncology monitoring experience, travel within the region, and the ability to work autonomously as the sole CRA on a study.

Qualifications

• 2+ years oncology monitoring experience required.
• Experience with Phase II/III oncology trials preferred.
• Ability to manage site relationships with minimal oversight.

Responsibilities

• Manage site monitoring activities for Phase II/III oncology trials (onsite and remote).
• Serve as primary clinical contact for assigned sites.
• Ensure protocol, GCP, ICH compliance in study conduct.
• Oversee site performance, data quality, and risk mitigation.
• Prepare monitoring documents, visit reports and follow-up communications.

Skills

Oncology monitoring

Site monitoring

Independent monitoring

Travel readiness

Education

Bachelor's degree not required (experience equivalent)

Job description

Piper Companies is seeking a Senior Clinical Research Associate (CRA) to support oncology clinical trials for a well-established organization within the clinical research industry. This Senior Clinical Research Associate (CRA) role is a 6-month remote contract (with extensions), full-service position. This individual will play a critical role overseeing Phase II and Phase III oncology studies, often functioning as the primary CRA on assigned trials.

Responsibilities of the Senior Clinical Research Associate include:

• Independently manage site monitoring activities for Phase II and III oncology trials, including a combination of onsite and remote visits averaging 8-10 onsite days per month.
• Serve as the primary clinical contact for assigned sites, building strong, long-term relationships and providing consistent support and guidance.
• Ensure study conduct aligns with protocol requirements, GCP, ICH guidelines, and applicable regulatory standards.
• Oversee site performance, data quality, and issue resolution while proactively identifying and mitigating risks.
• Prepare accurate and timely monitoring documentation, including visit reports and follow-up communications.

Qualifications for the Senior Clinical Research Associate include:

• Minimum of 2+ years of oncology monitoring experience with current expectations of approximately 3 years of independent monitoring.
• Hands-on experience supporting Phase II and Phase III clinical trials, ideally within a full-service model working with biotechnology clients.
• Ability to operate autonomously, including serving as the sole CRA on a study and managing site relationships with minimal oversight.
• Willingness and ability to travel regionally, reside within one hour of a major airport, and maintain required onsite visit expectations.
• Bachelor's degree not required for senior-level consideration if equivalent clinical research experience can be demonstrated.

Compensation for the Senior Clinical Research Associate:

Salary: $155,000-$175,000/year (USD)

Benefits: Medical, Dental, Vision, 401(k), and applicable paid leave

This job opens for applications on 10/30/26. Applications for this job will be accepted for at least 30 days from the posting date.

Keywords: clinical research, clinical trials, CRA, oncology, general medicine, GCP, ICH, regulatory compliance, site monitoring, CTMS, EDC, patient recruitment, protocol training, clinical documentation, data review, query resolution, clinical operations, FDA regulations, SOPs, quality oversight, risk-based monitoring, therapeutic areas.

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