Clinical Operations Lead - Trials, Data & TMF

Clinical Network Services; California (MO); Hybrid; USD 80,000 - 95,000; Full time

Job summary

Vanguard Clinical, Inc. is a CRO focused on high-quality clinical trial execution across multiple therapeutic areas.

The Clinical Operations Specialist (COS) supports and drives operational activities across Clinical Operations, SSU, TMF, Data Management, Vendor Oversight, Site Support, and study execution. This role expands autonomy and client-facing responsibilities with deep documentation and coordination duties.

Qualifications

• Minimum 3 years of clinical research experience in CRO, sponsor, or academic setting.
• Experience with eTMF, EDC, CTMS, IWRS, or study tracking tools.
• Strong working knowledge of ICH-GCP and GDP.
• Ability to independently manage multiple tasks with minimal supervision.
• Excellent communication and problem-solving skills.

Responsibilities

• Lead cross-functional coordination across the clinical trial lifecycle.
• Manage study trackers, enrollment metrics, and operational reporting.
• Prepare agendas, lead or co-lead portions of meetings, and finalize minutes and action items.
• Coordinate cross-functional workflows with CRAs, PMs, Data Management, SSU, Safety, and TMF teams.
• Support TMF, data quality, and audit readiness.

Skills

Clinical operations

Project management

Cross-functional collaboration

Documentation & QC

Communication skills

MS Office

Data review & reporting

Education

Bachelor of Science degree

Tools

eTMF

EDC

CTMS

IWRS

Study tracking tools

Job description

Vanguard Clinical, Inc. is a CRO focused on high-quality clinical trial execution across multiple therapeutic areas.

The Clinical Operations Specialist (COS) supports and drives operational activities across Clinical Operations, SSU, TMF, Data Management, Vendor Oversight, Site Support, and study execution. This role expands autonomy and client-facing responsibilities with deep documentation and coordination duties.