Clinical NGS Scientist I: Precision Medicine Lab

Tempus AI; Chicago (IL); On-site; USD 75,000 - 95,000; Full time

Job summary

Tempus AI is seeking a Scientist to develop, optimize, and validate molecular assays for deployment in a high-throughput clinical laboratory in Chicago. You will perform hands-on assay development for advanced molecular workflows and drive validation studies while collaborating with cross‑functional teams.

You will design experiments, interpret results, and support automation initiatives to improve laboratory workflows.

Qualifications

• Bachelor’s degree with 5+ years, or Master’s with 2+ years in molecular biology or assay development.
• Strong analytical, troubleshooting, and experimental design skills.
• Ability to interpret results via literature and SME input to refine design.
• Highly organized, detail oriented, and quality focused.
• Proven ability to learn quickly and adapt to new processes and workflows.
• Excellent collaboration and cross-team leadership; strong communication.

Responsibilities

• Perform hands-on assay development for molecular and NGS workflows in a regulated clinical lab.
• Design, execute and analyze R&D experiments with scientific rigor.
• Plan qualification and validation studies for reagents, instruments, methods.
• Interpret data, troubleshoot issues, and drive process improvements.
• Support automation initiatives to improve workflows in the lab.
• Maintain thorough documentation of methods, materials and results.
• Train and mentor junior staff and support new workflows.
• Collaborate across cross-functional teams and communicate with stakeholders.
• Manage multiple priorities in a fast-paced environment.
• Travel up to 10% as needed.

Skills

Molecular biology

Assay development

Experimental design

Complex data interpretation

Cross-functional collaboration

Documentation & SOPs

Education

Bachelor’s degree + 5+ years OR Master’s +2+ years

Tools

LIMS

Liquid handling robotics

Automation workflows

Job description

Tempus AI is seeking a Scientist to develop, optimize, and validate molecular assays for deployment in a high-throughput clinical laboratory in Chicago. You will perform hands-on assay development for advanced molecular workflows and drive validation studies while collaborating with cross‑functional teams.

You will design experiments, interpret results, and support automation initiatives to improve laboratory workflows.