Clinical Lead II: Rare Disease & Oncology Trials

Premier Research Group; United States; Remote; USD 120,000 - 180,000; Full time

Job summary

Premier Research Group in the United States is seeking a Clinical Lead II for Rare Disease/Oncology to drive site monitoring and sponsor communications while ensuring quality and timelines across trials.

You will oversee dashboards/central monitoring, manage data timelines and audit readiness, and bring hands-on RBM and CRO leadership across Rare Diseases and Oncology, including pediatric trials where applicable.

Qualifications

• Bachelor’s degree in a clinical, biological, scientific or health-related field, or equivalent experience.
• At least 2 years as a Clinical Lead in a CRO with on-site monitoring experience and RBM exposure.
• Experience in Rare Diseases and Oncology; CAR-T or Cell Gene Therapy experience preferred.
• Understanding of clinical financials including budgets, pass-throughs and resource management.

Responsibilities

• Serves as the initial point of contact for site management and monitoring quality concerns, initiating and overseeing sPIPs.
• Plans and presents sponsor calls, providing status updates on clinical deliverables.
• Oversees monitoring quality and site management through dashboards and central monitoring plans.
• Monitors operations metrics, timelines, data entry, deviations, queries, SDR/SDV backlog and visit report turnaround.
• Ensures audit readiness and supports site responses to audit findings and remediation.
• Escalates performance concerns through established channels including CRA/CM/SSU.

Skills

Onsite monitoring

Risk-Based Monitoring

Clinical trial management

Sponsor communications

Audit readiness

Education

Bachelor’s degree in clinical/biological field

Tools

Dashboard reporting

Budgeting

Job description

Premier Research Group in the United States is seeking a Clinical Lead II for Rare Disease/Oncology to drive site monitoring and sponsor communications while ensuring quality and timelines across trials.

You will oversee dashboards/central monitoring, manage data timelines and audit readiness, and bring hands-on RBM and CRO leadership across Rare Diseases and Oncology, including pediatric trials where applicable.