Clinical Genomics Scientist: Variant Curation & Analysis

Baylor Genetics; United States; On-site; USD 110,000 - 170,000; Full time

Job summary

Baylor Genetics is seeking a Clinical Genomics Scientist to curate variants and genes, analyze clinical genomics data, and summarize findings for clinical reports. The role supports laboratory directors and R&D with validation of cutting-edge technologies and software platforms.

The candidate will perform ACMG-guideline variant curation, HGVS-compliant nomenclature, and contribute to test validation, quality data assessments, and report drafting as part of an integrated genomics team.

Qualifications

• Requires PhD or MD in clinical medicine, genetics, molecular biology or equivalent.
• Or strong candidates with a Master’s degree and 2-4 years of variant curation experience.
• Preferred MB(ASCP) certification.

Responsibilities

• Curation (50%): curation of variants, genes, and gene-disease correlation following ACMG guidelines.
• Analysis (30%): analyzing clinical genomics data, selecting variants for curation/confirmation, variant nomenclature following HGVS guidelines.
• Other (20%): may involve clinical report drafting, test validation, process refinement, presenting findings, monitoring test turnaround time and task delegation.

Skills

Variant curation experience

Genomics data analysis

HGVS nomenclature

ACMG guidelines

Scripting languages

Bioinformatics analysis

Microsoft Office Suite

Education

PhD in clinical medicine/genetics/molecular biology or equivalent

MD in clinical medicine/genetics/molecular biology or equivalent

Master’s degree with relevant experience

MB(ASCP) certification

Tools

Microsoft Office Suite

Bioinformatics analysis

Variant effect prediction algorithms

Job description

Baylor Genetics is seeking a Clinical Genomics Scientist to curate variants and genes, analyze clinical genomics data, and summarize findings for clinical reports. The role supports laboratory directors and R&D with validation of cutting-edge technologies and software platforms.

The candidate will perform ACMG-guideline variant curation, HGVS-compliant nomenclature, and contribute to test validation, quality data assessments, and report drafting as part of an integrated genomics team.