Clinical Genetics & Pharmacogenomics Lead, Late-Stage Trials

Biogen; Cambridge (MA); On-site; USD 163,000 - 225,000; Full time

Benefits offered by this job

Health benefits

Competitive compensation

Stock purchase plan

Job summary

Biogen is seeking an Associate Scientific Director, Clinical Genetics, to lead clinical genetics and pharmacogenomics across Phase I–III programs. You will shape testing strategies, vendor partnerships, and data interpretation frameworks, driving integration of human genetics into development decisions.

You will collaborate with cross-functional teams to align genetics insights with trial design, regulatory requirements, and patient stratification, contributing to Biogen's differentiated

Qualifications

• PhD/MD/PharmD or equivalent in human genetics or pharmacogenomics.
• Minimum 8 years in human genetics/pharmacogenomics.
• Experience in industry settings with clinical development exposure.

Responsibilities

• Serve as clinical genetics and pharmacogenomics lead across trial programs (Phase I–III).
• Guide genetics strategies during late-stage research to clinical development.
• Advise on genetics objectives, patient identification, and testing considerations in protocols.
• Design genetic testing strategies including tech selection, labs, vendors, and data interpretation.
• Lead procurement for clinical genetics testing while addressing regulatory requirements.
• Support pharmacogenomic analyses and translate findings into development decisions.
• Develop practical, scientifically sound clinical trial processes incorporating genetics.
• Interpret genetic findings for clinical context to inform strategy.
• Apply large-scale genomic data to support multi-therapeutic program decisions.
• Identify reverse translational opportunities for target validation and stratification.
• Collaborate with cross-functional teams on data generation and regulatory considerations.

Skills

PhD/MD/PharmD

8+ years experience

Genetics & pharmacogenomics

Clinical development

Genetic testing strategies

Communication skills

Team collaboration

Regulatory knowledge

Education

PhD/MD/PharmD or equivalent in human genetics

Tools

Genomic data analysis tools

Job description

Biogen is seeking an Associate Scientific Director, Clinical Genetics, to lead clinical genetics and pharmacogenomics across Phase I–III programs. You will shape testing strategies, vendor partnerships, and data interpretation frameworks, driving integration of human genetics into development decisions.

You will collaborate with cross-functional teams to align genetics insights with trial design, regulatory requirements, and patient stratification, contributing to Biogen's differentiated