Clinical Development Director

Scorpion Therapeutics; United States; Remote; USD 250,000 - 450,000; Full time

Job summary

Scorpion Therapeutics is seeking a physician-scientist to lead the clinical development of first-in-class therapies targeting metabolism and immune-mediated diseases. The role focuses on advancing the early-stage pipeline and driving proof-of-mechanism studies.

You will design first-in-human protocols, oversee translational strategies, and support IND filings while building networks with KOLs and sites. Remote-enabled with potential travel as needed.

Qualifications

• MD with credibility in immune-mediated or metabolic disease.
• Proven experience leading early-phase clinical programs, esp. proof-of-mechanism.
• Strong translational and pharmacodynamic strategy expertise.
• Strategic, clinical, and scientific judgment.
• Entrepreneurial and collaborative mindset.

Responsibilities

• Design and execute first-in-human protocols.
• Develop translational and biomarker strategies.
• Support IND filing and regulatory planning.
• Build stakeholder networks including KOLs and sites.
• Contribute to scientific and platform narratives for investors.

Skills

Early-phase clinical program

Translational & PD strategy

Strategic clinical judgment

Collaborative mindset

Entrepreneurial mindset

Education

MD or equivalent

Job description

Role

Lead clinical development of first-in-class therapies targeting metabolism and autoimmune diseases, focusing on early-stage pipeline advancement.

Responsibilities

• design and execute first-in-human protocols
• develop translational and biomarker strategies
• support IND filing and regulatory planning
• build stakeholder networks including KOLs and sites
• contribute to scientific and platform narratives for investors

Requirements

• MD with credibility in immune-mediated or metabolic disease
• proven experience leading early-phase clinical programs, especially proof-of-mechanism studies
• strong translational and pharmacodynamic strategy expertise
• strategic, clinical, and scientific judgment
• entrepreneurial and collaborative mindset

High Value

• first-in-class, immune/metabolic indications, early clinical stage, proof-of-mechanism, IND support, translational focus, global KOL network

Work setup

remote; no specific travel details provided.