ChromExM Research Associate

University of California San Francisco; San Francisco (CA); On-site; USD 78,300 - 201,700; Full time

Job summary

The University of California San Francisco invites applications for a full or associate specialist in the Pownall Lab within Biochemistry and Biophysics.

The role concentrates on chromatin mechanisms in developing zebrafish embryos using advanced microscopy, requiring independent experimental design and execution, including zebrafish breeding, embryo microinjection, cell culture, cloning, and RNA synthesis.

Qualifications

• Master’s degree (or equivalent) or five to ten years of research experience
• Terminal degree (or equivalent) or ten or more years of research experience
• Experience in vertebrate embryology (fish, frog, or mouse)
• Broad expertise in advanced microscopy
• A record of research productivity with peer‑reviewed publications
• Experience working collaboratively in a shared research environment and supporting lab coordination
• Applicant materials must list current and/or pending qualifications on submission

Responsibilities

• Design and perform experiments independently; zebrafish breeding and embryo microinjection
• Mammalian cell culture, molecular cloning, and in vitro RNA synthesis
• Immunostaining, confocal microscopy, and expansion microscopy
• DNA and RNA FISH; quantitative image analysis
• Contribute to publications and grant applications
• Oversee day‑to‑day lab operations; order supplies; ensure safety compliance
• Assist with zebrafish care and husbandry as needed
• Develop ChromExM technology and manage collaborations
• Train and mentor lab members and collaborators
• Take ownership of experimental direction and troubleshooting

Skills

Vertebrate embryology

Advanced microscopy

Collaborative lab skills

Education

Master’s degree

Terminal degree

Tools

ChromExM

Confocal microscopy

Expansion microscopy

DNA/RNA FISH

Job description

The University of California San Francisco invites applications for a full or associate specialist in the Pownall Lab within Biochemistry and Biophysics.

The role concentrates on chromatin mechanisms in developing zebrafish embryos using advanced microscopy, requiring independent experimental design and execution, including zebrafish breeding, embryo microinjection, cell culture, cloning, and RNA synthesis.