Chemical Biology Postdoc: Probe Development & Drug Discovery

Dana-Farber Cancer Institute; Boston (MA); On-site; USD 72,000 - 76,000; Full time

Job summary

The Jones Lab at Dana-Farber Cancer Institute in Boston seeks a highly motivated Postdoctoral Research Fellow to develop chemical probes for therapeutic modalities. The role spans biochemical, biophysical, and cellular assays with in vivo validation, leveraging state-of-the-art facilities in chemistry, biophysics, and mass spectrometry.

Responsibilities include screening compounds, data interpretation, and exploring molecular modes of action, with contribution to publications and grants.

Qualifications

• PhD in chemical biology or related discipline required.
• Expert in protein preparation, biochemical assay development and compound screening.
• Experience in cell-based assay development and immunoblot.
• Evidence of consistent scientific innovation and publications in peer-reviewed journals.

Responsibilities

• Develop and apply biochemical, biophysical, and cellular assays for chemical probes with cellular and in vivo validation.
• Screen compounds and analyze data to inform probe quality and insights.
• Elucidate molecular modes of action of chemical probes.
• Maintain accurate lab records and contribute to publications and grants.

Skills

Protein preparation

Biochemical assay development

Compound screening

Cell-based assay development

Immunoblot

Excellent communication

Publications track record

Independent and collaborative work

Organizational skills

Data analysis

Education

PhD in chemical biology or related discipline

Job description

The Jones Lab at Dana-Farber Cancer Institute in Boston seeks a highly motivated Postdoctoral Research Fellow to develop chemical probes for therapeutic modalities. The role spans biochemical, biophysical, and cellular assays with in vivo validation, leveraging state-of-the-art facilities in chemistry, biophysics, and mass spectrometry.

Responsibilities include screening compounds, data interpretation, and exploring molecular modes of action, with contribution to publications and grants.