Cell Therapy Research Associate — Automation & Analysis

Vertex Pharmaceuticals LLC

Boston (MA)

On-site

USD 48,000 - 52,000

Full time

14 days+
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Qualifications

  • BS or MS in Analytical Chemistry, Biochemistry, Cell & Molecular Biology or related field.

Responsibilities

  • Carry out routine cell culture for primary cells, stem cells and other mammalian lines to support analytical testing.
  • Provide analytical testing support for cell-based assays (cell count, viability, high throughput fluorescence, flow cytometry).
  • Assist with daily automated runs and monitor automation systems for efficiency.
  • Perform sample testing using ELISA, PCR and flow cytometry.
  • Coordinate shipment handling and track inventory for samples/reagents.

Skills

Pipetting skills
Aseptic cell culture
Diverse cell types culture
Robotic liquid handlers
SOP adherence
Cross-functional collaboration
Lab safety & GLP
MS Office proficiency
Under pressure performance

Education

BS/MS in Analytical Chemistry, Biochemistry, Cell & Molecular Biology

Tools

Hamilton/other robotic liquid handlers
Fluent Gx, VENUS software
ELN/LIMS familiarity

Job description

Key Duties and Responsibilities:

  • Carry out routine cell culture both manually and automated of primary cells, stem cells and other mammalian cell lines to support analytical testing for Vertex’s preclinical, clinical and next generation cell therapy programs.
  • Provide analytical testing support for cell-based assays like cell count and viability assay, high throughput fluorescence cell-based assay and flow cytometry assay using automation tools like liquid handlers, flow cytometers and high content microscopes.
  • Assist analytical development teams with setting up, monitoring, and successfully completing daily automated runs and integrated systems and continuously monitor the health of automation systems and evaluate their efficiency and effectiveness.
  • Perform sample testing for analytical development team by using a variety of techniques; (e.g- Cell Culture, Flow Cytometry, ELISA, PCR.)
  • Coordinate shipment handling, and reagents from internal and external sources and track inventory for samples and reagents as needed for several projects.
  • Support Monday to Friday with occasional off-schedule days, and second shift/late evening coverage as required for process and analytical development teams on several assays as required and flexible to travel between sites within 2.0 mile distance.
  • Be a strong team player contributing to group priorities and deliverables and possess excellent attention to detail
  • Ability to work effectively in a fast-paced environment with changing priorities
  • Maintain excellent written documentation of completed experiment (ELN) and maintain knowledge share systems (MS-Teams and share points).
  • Ability to follow and understand SOPs and review protocols or reports as needed along with good analytical understanding for data interpretation.
  • Assist with lab organization and compliance with lab safety protocol and perform other duties as assigned.

Education level and/or relevant experience(s)

Required:BS or MS in Analytical Chemistry, Biochemistry, Cell & Molecular Biology, or related discipline with BS 0-2 years experience or MS with 0 years experience

Preferred: Relevant industry experience in the biologics or cell and gene therapy space.

Knowledge and skills (general and technical)

Required:

  • Possesses excellent pipetting skills.
  • Strong knowledge of aseptic cell culture technique.
  • Has experience culturing multiple different cell types including but not limited to stem cells, primary cells and cell lines.
  • Experience with or understanding robotic liquid handers (Hamilton or other) and their operating software (Fluent Gx, VENUS, or other) for automated sample preparation.
  • Ability to follow SOPs and carry out cell culture assays.
  • Has excellent communication skills and is effectively able to work collaboratively with cross-functional teams.
  • Strong organizational skills and good attention to detail.
  • Possess standard lab safety regulations and work in GLP like laboratory
  • environment
  • Ability to utilize Microsoft PowerPoint, Excel and Word to perform tasks as
  • Able to perform successfully under pressure while prioritizing and handling multiple projects or priorities within required timelines.

Preferred:

Industry experience in cell and gene therapy space.

  • Experience with sample management and ELN/LIMS systems.
  • Experience working withpluripotent/hematopoieticstem cells.
  • Knowledge of automation tools
Pay Range

$35/hr. - $38/hr.

Shift/Hours
  • Support Monday to Friday with occasional weekends
  • This is an onsite position at our Boston FP site and occasional travel to Boston LC site
Requisition Disclaimer

This job posting is for a temporary role with a third-party agency partner on assignment at Vertex Pharmaceuticals (“Vertex”). The individual selected for this role will be offered the role as an employee of a third- party agency partner; compensation, medical benefits, fringe benefits and other terms and conditions of employment shall be presented by the third-party agency partner upon offer. The pay rate range provided is a reasonable estimate of the anticipated compensation range for this job at the time of posting. The actual pay rate will be based on a number of factors, including skills, competencies, experience, location and/or being pursued and other job-related factors permitted by law. In addition, this role will be eligible for overtime pay, in accordance with federal and state requirements

No C2C or Third-Party Vendors

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