Cell Therapy Manufacturing Supervisor – Lead Key Production

Orcabiosystems; Sacramento (CA); On-site; USD 95,000 - 140,000; Full time

Benefits offered by this job

Pre-IPO equity

Annual bonus

Medical insurance

PTO & 401(k)

Parental leave

Job summary

Orca Bio is seeking a Supervisor, Commercial Manufacturing to lead a cell therapy production team at our Sacramento facility. The role focuses on ensuring adherence to quality standards, regulatory requirements and aseptic production techniques across shifts.

Responsibilities include supervising staff, coordinating daily activities, training, and enforcing SOPs, while partnering with QA/QC to ensure compliant production and accurate documentation.

Qualifications

• B.S. degree required in biology or related field.
• 2+ years of supervisory or team experience.
• M.S. degree preferred.
• Prior experience in cell therapy or other advanced biologics.
• Familiarity with deviation investigations, CAPAs and change control processes.
• Ability to gown and work in clean rooms.

Responsibilities

• Supervise a team of associates during shift operations.
• Coordinate daily manufacturing activities to meet schedule, and quality and compliance goals.
• Execute and enforce cGMP‑compliant SOPs, batch records, and safety procedures.
• Provide on‑floor training, mentorship, and performance feedback to production staff.
• Monitor and troubleshoot production activities and equipment, escalating as needed.
• Partner with QA and QC to support in‑process checks, deviation investigations, and batch record reviews.
• Maintain real‑time, accurate documentation of manufacturing processes and equipment use.
• Support continuous improvement initiatives to increase reliability and efficiency.
• Participate in CAPA and deviation investigations related to manufacturing activities.

Skills

Supervisory experience

Aseptic manufacturing

cGMP compliance

Quality collaboration

Documentation accuracy

Education

B.S. in Biology

M.S. in Biology (preferred)

Job description

Orca Bio is seeking a Supervisor, Commercial Manufacturing to lead a cell therapy production team at our Sacramento facility. The role focuses on ensuring adherence to quality standards, regulatory requirements and aseptic production techniques across shifts.

Responsibilities include supervising staff, coordinating daily activities, training, and enforcing SOPs, while partnering with QA/QC to ensure compliant production and accurate documentation.