Cell Manufacturing Assistant, Cell Therapy Core

msk; New York (NY); On-site; USD 54,000 - 84,000; Full time

Job summary

Memorial Sloan Kettering Cancer Center (MSK) is seeking a meticulous Cell Manufacturing Assistant for the Cell Therapy Core Facility on-site at NYC. You will support cGMP production of NK, TCR, and T cell products and assist in tech transfer and quality control of cell banks.

The role requires hands-on molecular and cellular biology experience, strong documentation skills, and the ability to work under GDP/cGMP standards in a fast-paced environment.

Qualifications

• BA/BS or higher with related experience; cGMP or clinically regulated environment preferred.
• Experience with molecular and/or cellular biology techniques.
• Knowledge of basic computer applications and ability to use MS Office software

Responsibilities

• Participate in the cGMP Production of large-scale clinical-grade products such as, NK, TCR, and T cell products.
• Assist in the production/development and quality control of ancillary cells, such as master cell banks.
• Analyze gene expressions in cell lines, primary cell lines, and research samples using FACS, PCR, qPCR, etc
• Participate in process validation and tech transfer activities
• Participate in planning and discussion of laboratory projects with team leaders and managers
• Operate and maintain complex laboratory equipment such as FACS machine, qPCR machine, cell washers, and bioreactors
• Complete all documentation per GDP and cGMP regulation per CTCF's SOPs and maintaining detailed experimental records
• Proactively participate in data analysis, data summary, data evaluation, and maintenance of corresponding databases in an accurate and timely fashion
• Development, writing and updating of SOPs and material lists
• General lab upkeep and organization

Skills

cGMP experience

Biotech knowledge

Molecular biology

Cellular biology

MS Office

Education

BA/BS with five years related experience

MA/MS with three years related experience

Tools

FACS

qPCR

Bioreactors

Cell washers

Job description

About Us:

The people of Memorial Sloan Kettering Cancer Center (MSK) are united by a singular mission: ending cancer for life. Our specialized care teams provide personalized, compassionate, expert care to patients of all ages. Informed by basic research done at our Sloan Kettering Institute, scientists across MSK collaborate to conduct innovative translational and clinical research that is driving a revolution in our understanding of cancer as a disease and improving the ability to prevent, diagnose, and treat it. MSK is dedicated to training the next generation of scientists and clinicians, who go on to pursue our mission at MSK and around the globe.

Exciting Opportunity at MSK:

TheCell Therapy Core Facility (CTCF) develops, validates, and implements procedures critical to gene transfer-related clinical research including: genetic engineering and ex vivo transduction of patient cells, cell line development, vector production, R&D and process development work relating to vector production and transduction of patient cells, analysis of gene transfer efficiency and transgene expression in patient cells. BTCF enables the translation of innovative research concepts into clinically relevant studies, supporting the development of new strategies for understanding and applying gene-based therapies!

We are seeking a meticulous and proactive individual who has excellent organizational skills and strong attention as a Cell Manufacturing Assistant to assist in the aforementioned areas under general supervision.

Role Overview:

• cGMP Manufacturing: Participate in the cGMP Production of large-scale clinical-grade products such as, NK, TCR, and T cell products
• Tech Transfer activities : Assist in the production/development and quality control of ancillary cells, such as master cell banks
• Analyze gene expressions in cell lines, primary cell lines, and research samples using FACS, PCR, qPCR, etc
• Participate in process validation and tech transfer activities
• Participate in planning and discussion of laboratory projects with team leaders and managers
• Operates and maintain complex laboratory equipment such as FACS machine, qPCR machine, cell washers, and bioreactors
• Complete all documentation per GDP and cGMP regulation per CTCF's SOPs and maintaining detailed experimental records
• Proactively participate in data analysis, data summary, data evaluation, and maintenance of corresponding databases in an accurate and timely fashion
• Development, writing and updating of SOPs and material lists
• General lab upkeep and organization

Key Qualifications:

• BA/BS with five (5) years related experience or MA/MS with three (3) years related experience; previous experience in cGMP or clinically regulated environment and knowledge of biotechnologies are strongly preferred.
• Must have experience with molecular and/or cellular biology techniques.
• Knowledge of basic computer applications and ability to use MS Office software

Core Skills:

• Excellent communication skills and the ability to interact across all levels in a confident, professional manner.
• Ability to independently resolve issues and questions.
• Flexible to adapt to new projects as required for the support of the group.
• Capable of successfully prioritizing tasks.
• A good decision-maker, with proven success at taking initiative and making timely decisions that keep the organization moving forward.
• Ability to work in a fast-paced environment with a positive attitude
• Ability to carry out assignments in a thorough, conscientious fashion.
• Ability to follow detailed instructions, maintain accurate records and notes.
• Ability to work well in a team environment.

Additional Information :

• Location: 417 E 68th St, NYC
• Schedule: On-site
• Reporting to the Supervisor, CTCF

Helpful Links :

• Compensation Philosophy
• Benefits
• Pay Range: $39.54 - $61.23
• FSLA Status: Non-Exempt

Closing :

At MSK, we believe in fair, competitive pay that reflects your job, experience, and skills.

MSK is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration without regard to race, color, gender, gender identity or expression, sexual orientation, national origin, age, religion, creed, disability, veteran status or any other factor which cannot lawfully be used as a basis for an employment decision.

Federal law requires employers to provide reasonable accommodation to qualified individuals with disabilities. Please tell us if you require a reasonable accommodation to apply for a job or to perform your job. Examples of reasonable accommodation include making a change to the application process or work procedures, providing documents in an alternate format, using a sign language interpreter, or using specialized equipment.