Business Performance Director

BioSpace; Washington (District of Columbia); Remote; USD 180,000 - 260,000; Full time

Job summary

Amgen seeks a strategic Business Performance Director to shape transformation programs and lead enterprise change initiatives. You will build business cases, develop transformation strategies, and partner with senior leaders to realize value across regions.

The role requires experience in large-scale transformations, sponsorship development, and cross-functional leadership, with a focus on delivering measurable outcomes and sustained performance.

Qualifications

• Requires doctorate/master/bachelor with 4–9 years in Business Transformation, Organizational Change Management, Strategic Planning, or Program Management.
• Experience leading large transformation programs and change management initiatives.
• Experience influencing a global, matrixed organization and leading enterprise change.

Responsibilities

• Lead development of executive-level business cases and financial analyses.
• Develop and oversee value realization plans and governance with senior leaders.
• Manage change management strategies across processes, technology, and workforce.

Skills

Transformation management

Financial acumen

Project management

Communication skills

Leadership

Stakeholder engagement

Education

Doctorate degree

Master’s degree

Bachelor’s degree

Job description

Join Amgens Mission of Serving Patients

At Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do.

Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. Amgen is advancing a broad and deep pipeline and portfolio of medicines to treat heart disease, obesity and obesity-related conditions, rare diseases, inflammatory conditions and cancer. As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Business Performance Director

What you will do

Lets do this. Lets change the world. In this vital role you will build business cases for approval by senior executives, independently develop transformation strategies for key initiatives, and lead initiatives through the transformation process. This will include developing value realization measures, managing the value realization process, and determining the best use of transformation tools and methods to help initiatives achieve intended outcomes.

Candidate should have experience leading change management for large business transformation programs and initiatives. They will develop and implement complex change management strategies and plans related to changes to organizational structures, processes, and technologies across multiple timeframes and impact. This requires expertise in sponsorship development, change communications, capability development, and behavior change. Must be able to oversee others execution of associated tactics.

This role will lead senior leaders and teams through structured problem solving using Disciplined Approach methodology to drive alignment around critical issues, options, and solutions. These problems will often be cross functional in nature. They will be a thought partner for leaders and work across technology, process, andbusinesstosupport solution implementation.

Will Be Accountable For Independently Delivering The Following

• Effective executive level business cases, including financial analysis
• Establishing initiative governance with senior leaders
• Change team management and facilitation
• Interdependency identification and management
• Establish realization measures and targets
• Develop and manage value realization plan
• Assess and mitigate risks to delivery and value realization
• Identify impacted populations and expected level of disruption
• Fully Remote with onsite presence required for critical workshops and planning sessions.

Responsibilities

• Maintain 12 quarter plan for initiatives and programs
• Integrate key activities and milestones across initiatives
• Maintain measures that track progress and can be used in communications with Executives
• Develop and manage key milestone readiness and release readiness processes for all initiatives
• Lead the end-to-end organizational change management for transformation programs, integrating change strategy, stakeholder engagement, communications, and training to drive adoption and sustained performance.
• Design and execute integrated change management plans spanning process, technology, workforce, risk, and communications to drive clarity andcoordinatedexecution.
• Develop and execute capability frameworks that clarify roles, expectations, and leadership readiness to support successful operating model adoption.
• Establish governance and oversee delivery of role-based learning and training programs, ensuring alignment to transformation priorities and role requirements.
• Manage internal and external partners to deliver scalable, high-quality learning experiences, including oversight of scope, deliverables, quality, and timing.
• Establish structured communications strategies and engagement rhythms to enable transparency, alignment, and stakeholder commitment throughout the transformation lifecycle.
• Monitor and report capability building, training and change metrics to inform leadership decisions and continuously improve the change approach.
• Standardize and scale capability enablement processes to ensure consistency, efficiency, and sustainability across the organization.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The strategic and transformational leader we seek is an experienced business performance professional with the following qualifications.

Basic Qualifications

• Doctorate degree and 4 years of Business Transformation, Organizational Change Management, Strategic Planning, or Program Management experience
• OR
• Masters degree and 7 years Business Transformation, Organizational Change Management, Strategic Planning, or Program Management experience
• OR
• Bachelors degree and 9 years of Business Transformation, Organizational Change Management, Strategic Planning, or Program Management experience

Preferred Qualifications

• Strong transformation skillset
• Financial acumen
• Project management skills
• Strong organizational skills, including ability to follow assignments through to completion
• Collaborate and communicate with initiative leadership teams
• Strong communication (both written and oral), facilitation, and presentation skills
• Strong skill in working independently and to effectively interact with various levels
• Demonstrate the Amgen Values and Leadership Characteristics
• Experienceoperatingin regulated, quality-sensitive environments (biopharma preferred) with understanding of transformation delivery and business impact.
• Ability to integrate learning, knowledge, and change management to drive sustained performance.
• Demonstrated ability to influence a global, matrixed organization and lead enterprise change initiatives.
• Experience designing scalable workforce processes, governance frameworks, and/or capability strategies.
• Strong program/project management capability, including navigating ambiguity, driving alignment, and delivering measurable outcomes.
• Strong written and verbal communication skills, including executive-level messaging and organizational storytelling.

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, well support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In Addition To The Base Salary, Amgen Offers a Total Rewards Plan, Based On Eligibility, Comprising Of Health And Welfare Plans For Staff And Eligible Dependents, Financial Plans With Opportunities To Save Towards Retirement Or Other Goals, Work/life Balance, And Career Development Opportunities That May Include

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales‑based incentive plan
• Stock‑based long‑term incentives
• Award‑winning time‑off plans
• Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

Amgen is an Equal Opportunity employer. We make all employment decisions without regard to race, color, religion, sex or any other characteristic protected by applicable law.

We provide reasonable accommodations to applicants and employees with disabilities, consistent with legal requirements. Please contact us to request accommodation.

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.