Brain Tissue Processing & Electrophysiology Associate

Allen Cell; Seattle (WA); Hybrid; USD 54,000 - 66,000; Full time

Benefits offered by this job

Medical, dental, vision insurance

401(k) plan

Paid time off

Job summary

The Allen Institute seeks a Research Associate I in Seattle to support tissue processing and electrophysiology projects. You will generate high-quality patch-clamp electrophysiology and transcriptomic data, perform tissue dissections, and handle multiple species' brain tissue in a high-throughput lab, following SOPs.

Responsibilities include surgical procedures, tissue processing, QC criteria, data reporting, and collaboration with a dynamic team.

Qualifications

• Bachelor's degree in a life science or related field.
• 1+ years of related work experience and/or training preferred.
• Exceptional manual dexterity and attention to detail.
• Basic knowledge of mouse neuroanatomy, electrophysiology, genetics, flow cytometry, RNA sequencing, and/or cell biology.
• Experience working with mice, NHP, human or other tissue samples.
• Experience with fluorescence and/or dissection microscopy.
• Ability to critically interpret and analyze scientific data.
• Intermediate level ability with Microsoft Office suite and the ability to learn other custom software systems.

Responsibilities

• Perform acute surgical procedures and tissue dissections.
• Handling of mice.
• Processing mouse, human, non-human primate (NHP), and brain tissue.
• Perform patch-seq experiments from mouse, NHP and human brain slice preparations.
• Apply established quality control (QC) criteria in all experimental designs; help develop new analytical criteria and insights from electrophysiological, molecular biology and imaging data.
• Pilot and optimize tissue preparations for advanced imaging techniques.
• Work in dynamic core facilities with tight deadlines.
• Dissociation and preparation of single cell/nuclei samples for analysis.
• Cell and tissue histological staining.
• Follow SOPs, good laboratory practices, and regulatory requirements.
• Maintain accurate laboratory documentation and reporting using established methods.
• Work with supervisor to appropriately manage time and prioritize tasks.
• Contribute to a cohesive and efficient team environment.
• Exposure to and handling of laboratory animals required.
• Perform euthanasia, surgical procedures, and tissue collections.
• Occasional lifting up to 30 pounds.
• Fine motor movements in fingers/hands to operate computers and lab equipment; repetitive motion with lab equipment.
• Push/pull a cart.
• Stooping, bending, crouching, sitting.

Skills

Manual dexterity

Attention to detail

Data analysis

Independent working

Team collaboration

Education

Bachelor's degree in life science or related field

Tools

Dissection microscopy

Fluorescence microscopy

Microsoft Office

Job description

The Allen Institute seeks a Research Associate I in Seattle to support tissue processing and electrophysiology projects. You will generate high-quality patch-clamp electrophysiology and transcriptomic data, perform tissue dissections, and handle multiple species' brain tissue in a high-throughput lab, following SOPs.

Responsibilities include surgical procedures, tissue processing, QC criteria, data reporting, and collaboration with a dynamic team.