BioProcess Engineer

BioSpace; Waltham (MA); On-site; USD 130,000 - 190,000; Full time

Job summary

BioSpace in Waltham, MA, is seeking a Process Engineering and Innovation Lead to drive evaluation and integration of cutting-edge technologies for mRNA process development and manufacturing. You will lead proof-of-concept studies and develop technology roadmaps aligned with platform strategy.

The role requires PhD with 2+ years, MS with 4+ years, or BS with 5+ years in bioprocess engineering, and emphasizes GMP-compliant process development and cross-functional leadership.

Qualifications

• Experience implementing new technologies in bioprocess environments with measurable outcomes.
• Proven track record scaling up processes from laboratory to clinical or commercial manufacturing.
• Strong understanding of bioprocess engineering principles and GMP environments.

Responsibilities

• Identify and evaluate emerging technologies for mRNA process development and manufacturing.
• Lead proof-of-concept studies and create technology roadmaps aligned with platform strategy.
• Drive process intensification to improve efficiency, yield, and quality while reducing waste.
• Ensure technology transfer is aligned with scale-up for clinical and commercial manufacturing.
• Collaborate with external technology providers, Manufacturing, and Quality teams for GMP compliance.
• Conduct risk assessments and quantify impact on KPIs and cost of goods.

Skills

Bioprocess engineering

Technology transfer

GMP knowledge

Education

Bachelor's, Master's, or PhD in Chemical/Bioprocess/Biochemical Engineering

Job description

About the Job

As Process Engineering and Innovation Lead within our mRNA Center of Excellence, you'll drive the evaluation and integration of cutting-edge technologies while ensuring they meet scale-up and commercial manufacturing requirements. Ready to get started?

Job Title: BioProcess Engineer
Location: Waltham, MA

Main Responsibilities

• Identify, evaluate, and integrate emerging technologies to enhance mRNA process development and manufacturing, leading proof-of-concept studies and creating technology roadmaps aligned with platform strategy
• Drive process intensification initiatives to improve efficiency, yield, and quality while reducing process steps, minimizing waste, and implementing continuous processing strategies where applicable
• Ensure new technologies and innovations are compatible with scale-up requirements, developing models and strategies for transitioning from laboratory to clinical and commercial manufacturing
• Lead next-generation mRNA platform development, establishing performance metrics and coordinating cross-functional efforts to integrate innovations across the organization
• Collaborate with external technology providers, academic partners, Manufacturing, and Quality teams to stay current with industry innovations and ensure GMP compliance
• Conduct risk assessments, quantify impact on key performance metrics and cost of goods, and lead technology transfer activities for innovative processes

Education

• Bachelor's, Master's, or PhD degree in Chemical Engineering, Bioprocess Engineering, Biochemical Engineering, or related technical field

About You

• PhD with 2+ years, MS with 4+ years, or BS with 5+ years of relevant industrial experience in bioprocess engineering or related fields

Experience and Technical Skills

• Demonstrated success implementing new technologies in bioprocess environments with measurable outcomes
• Proven track record scaling up processes from laboratory to clinical or commercial manufacturing
• Strong understanding of bioprocess engineering principles, unit operations, and process development in GMP environments

Preferred Qualifications

• Knowledge of regulatory requirements for process changes and technology implementation
• Background in modeling, data analysis, or automation is a plus

Soft Skills

• Excellent project management and cross-functional leadership abilities with strong influence skills
• Outstanding problem-solving capabilities with an innovative, forward-thinking mindset
• Strong communication skills to articulate complex technical concepts to diverse audiences

Languages

• Excellent knowledge of English (spoken and written)
• French is a plus

Why choose us?

• Bring the miracles of science to life alongside a supportive, future focused team.
• Discover endless opportunities to grow your talent and drive your career, whether its through a promotion or lateral move, at home or internationally.
• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks gender-neutral parental leave.
• Be part of a pioneering biopharma company that engages patients early in drug development and uses their insights to design studies that reflect real-world needs.
• Work at the forefront of drug discovery, harnessing cutting-edge AI, data, and digital platforms to push the boundaries of science.
• Help improve the lives of millions of people globally by making drug development quicker and more effective.

Equal Opportunity Statement

Sanofi US Services and its U.S. affiliates are Equal Opportunity employers committed to a culturally inclusive workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

Compensation and Benefits

All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.