BioProcess Engineer

(2605) Sanofi Vaccines US Inc.; Waltham (MA); On-site; USD 101,000 - 145,000; Full time

Job summary

Sanofi Group is seeking a BioProcess Engineer in Waltham, MA to lead evaluation and integration of advanced technologies for scalable mRNA process development and manufacturing.

You will drive process intensification, collaborate with cross-functional teams, and ensure regulatory compliance as you bridge lab work with commercial production. This role emphasizes innovation, data-driven decision making, and hands-on optimization.

Qualifications

• Bachelor's, Master's, or PhD in Chemical/Bioprocess/Biochemical Eng or related field.
• PhD with 2+ years, MS with 4+ years, or BS with 5+ years of relevant industrial experience.

Responsibilities

• Identify, evaluate, and integrate emerging technologies to enhance mRNA process development and manufacturing.
• Drive process intensification to improve efficiency, yield, and quality while reducing steps and waste.
• Ensure new technologies are compatible with scale-up, developing models for transitioning to clinical and commercial manufacturing.
• Lead next-generation mRNA platform development and coordinate cross-functional efforts.
• Collaborate with external providers, Manufacturing, and Quality teams to stay current with GMP compliance.
• Conduct risk assessments, quantify impact on KPIs and cost of goods, and lead tech transfer activities.

Skills

Bioprocess engineering

Process scale-up

GMP compliance

Modeling / data analysis

Automation awareness

Education

Bachelor's degree in Chemical Engineering

Master's degree in Bioprocess Engineering

PhD in Bioprocess engineering

Tools

Modeling software

Data analysis tools

Automation tools

Job description

BioProcess Engineer

Location: Waltham, MA

About the job

As Process Engineering and Innovation Lead within our mRNA Center of Excellence, you'll drive the evaluation and integration of cutting‑edge technologies while ensuring they meet scale‑up and commercial manufacturing requirements. Ready to get started? Join our mRNA Center of Excellence where Sanofi is accelerating innovation in the mRNA space. With our long‑standing expertise in developing and commercializing vaccines and innovative medicines globally, we're building a robust technological foundation that bridges conceptual innovation with practical manufacturability. You'll work at the intersection of process engineering and innovation, helping transform how we develop and manufacture next‑generation mRNA therapies. Join the engine of Sanofi’s mission — where deep immunoscience meets bold, AI‑powered research. In R&D, you'll drive breakthroughs that could turn the impossible into possible for millions. About Sanofi: We're an R&D‑driven, AI‑powered biopharma company committed to improving people's lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people's lives.

Main responsibilities

• Identify, evaluate, and integrate emerging technologies to enhance mRNA process development and manufacturing, leading proof‑of‑concept studies and creating technology roadmaps aligned with platform strategy.
• Drive process intensification initiatives to improve efficiency, yield, and quality while reducing process steps, minimizing waste, and implementing continuous processing strategies where applicable.
• Ensure new technologies and innovations are compatible with scale‑up requirements, developing models and strategies for transitioning from laboratory to clinical and commercial manufacturing.
• Lead next‑generation mRNA platform development, establishing performance metrics and coordinating cross‑functional efforts to integrate innovations across the organization.
• Collaborate with external technology providers, academic partners, Manufacturing, and Quality teams to stay current with industry innovations and ensure GMP compliance.
• Conduct risk assessments, quantify impact on key performance metrics and cost of goods, and lead technology transfer activities for innovative processes.

About you

Education

• Bachelor's, Master's, or PhD degree in Chemical Engineering, Bioprocess Engineering, Biochemical Engineering, or related technical field.
• PhD with 2+ years, MS with 4+ years, or BS with 5+ years of relevant industrial experience in bioprocess engineering or related fields.

Experience & Technical Skills

• Demonstrated success implementing new technologies in bioprocess environments with measurable outcomes.
• Proven track record scaling up processes from laboratory to clinical or commercial manufacturing.
• Strong understanding of bioprocess engineering principles, unit operations, and process development in GMP environments.
• Knowledge of regulatory requirements for process changes and technology implementation.
• Background in modeling, data analysis, or automation is a plus.

Preferred Qualifications

• Knowledge of regulatory requirements for process changes and technology implementation.
• Background in modeling, data analysis, or automation is a plus.

Soft Skills

• Excellent project management and cross‑functional leadership abilities with strong influence skills.
• Outstanding problem‑solving capabilities with an innovative, forward‑thinking mindset.
• Strong communication skills to articulate complex technical concepts to diverse audiences.

Languages

• Excellent knowledge of English (spoken and written).
• French is a plus.

Why choose us?

Bring the miracles of science to life alongside a supportive, future focused team. Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally. Enjoy a thoughtful, well‑crafted rewards package that recognizes your contribution and amplifies your impact. Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least fourteen weeks’ gender‑neutral parental leave. Be part of a pioneering biopharma company that engages patients early in drug development and uses their insights to design studies that reflect real‑world needs. Work at the forefront of drug discovery, harnessing cutting‑edge AI, data, and digital platforms to push the boundaries of science. Help improve the lives of millions of people globally by making drug development quicker and more effective.

Sanofi US Services and its U.S. affiliates are Equal Opportunity employers committed to a culturally inclusive workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

The salary range for this position is: $100.500,00 - $145.166,66. All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.

We are an R&D driven, AI-powered biopharma company committed to improving people’s lives and creating compelling growth. Our team is guided by one purpose: we chase the miracles of science to improve people’s lives. We want to build a healthier, more resilient world, and turn the impossible into the possible by discovering, developing, and delivering medicines and vaccines for millions of people around the world. Discover more about us visiting www.sanofi.com or via our movie We are Sanofi Start a career that makes a difference. Reinvention is in our DNA. It’s what drove our evolution from a small French enterprise to one of the world’s leading biopharma companies. Whether it’s using AI to shorten drug‑discovery times or building trust in healthcare, you could be helping our teams make life better for patients, partners, and communities. This is where you grow your career. We open the door for you to explore new opportunities, push your limits, and connect with people who are driven by a shared purpose: we chase the miracles of science to improve people’s lives.