Biopharmaceutical Production Manager

GlaxoSmithKline; King of Prussia (PA); On-site; USD 95,000 - 140,000; Full time

Job summary

GlaxoSmithKline is seeking a Production Manager to lead 4 shift operations in a 24/7 biopharmaceutical manufacturing facility. You will oversee production supervisors and front-line staff, ensuring safe, compliant, and cost-effective execution of processes while collaborating with department heads on improvements for current and future products.

The role requires a strong track record in biopharmaceutical manufacturing, quality systems, and team leadership, with emphasis on achieving site KPIs

Qualifications

• Bachelor's degree in chemical/biomedical/engineering field.
• 7+ years in biopharmaceutical/biotech industry.
• 3+ years in a management role overseeing direct and indirect reports.
• Master's degree in biological sciences or engineering (preferred).

Responsibilities

• Lead 4 shift operations in a 24/7 facility.
• Ensure compliance with manufacturing, safety, and environmental regulations (QMS/EHS, CFR/cGMP, OSHA, local/state/federal requirements).
• Oversee documentation practices, approve Batch Documents, and ensure SOP and logbooks are maintained within compliance.
• Set departmental priorities using operational data and staff capacity.
• Meet department and site KPIs for safety, quality, and supply.
• Develop workforce plans for staff development and performance management.

Skills

Biopharmaceuticals

Bioprocessing

Cell Line Development

Drug Development

Experimental Methods

Molecular Cell Biology

Pharmaceutical Industry

Pharmaceutical Manufacturing

Quality by Design

Regulatory Submissions

Simulation Models

Technical Writing

Technology Transfer

Education

Bachelor's degree in Chemical, Mechanical, Biomedical, Engineering or Biotechnology field

Master's degree in biological sciences, or an engineering discipline

Job description

This role is part of a dynamic operations team delivering vital medicines to patients globally. The Production Manager upholds GSK Values and Expectations, working collaboratively with colleagues and support groups. Reporting to the Value Stream Lead and Site Leadership, they are responsible for ensuring safe, compliant, and cost-effective execution of biopharmaceutical processes, and coordinating with department heads on projects to enhance performance for current and future products.

This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:

• Carry out tasks and interactions in accordance with GSK's core values: Accountability for Impact, Ambition for Patients, and Doing the Right Thing.
• Follow GSK's leadership expectations by focusing on priorities, motivating others, and supporting team growth to encourage high performance.
• Partner with the NPI leads and support team managers for the successful implementation of new products and equipment.
• Manage 4 shift operations in a 24/7 facility, overseeing production supervisors, specialsts, and front-line staff.
• Ensure compliance with manufacturing, safety, and environmental regulations (GSK QMS/EHS, CFR/cGMP, OSHA, local/state/federal requirements).
• Oversee documentation practices, approve Batch Documents, and ensure SOP and logbooks are maintained and within compliance, and ensure sufficient data integrity controls in place.
• Set departmental priorities using operational data and staff capacity.
• Meet department and site KPIs for safety, quality, and supply.
• Approve safety and compliance investigations; promote transparency and a values-driven culture.
• Hold teams accountable for cross-functional activities like engineering, validation, and tech transfer studies.
• Recommend updates to digital platforms.
• Develop workforce plans for staff development and performance management.
• Define production and staffing requirements to meet schedules.

Why you?

Basic Qualifications:

• Bachelor's degree in Chemical, Mechanical, Biomedical, Engineering or Biotechnology field
• 7+ years of experience in biopharmaceutical, biotechnology, or a related technology-driven industry
• 3+ years in a management role overseeing both direct and indirect reports.

Preferred Qualifications:

If you have the following characteristics, it would be a plus:

• A Master's degree in biological sciences, or an engineering discipline
• 5 or more years of experience in large-scale manufacturing preferred
• Proficient verbal and written communication abilities are essential, as is the capacity to collaborate effectively within a team environment.
• Experience in hands-on operations, previous people leadership roles, and participation in responsibilities beyond production operations are preferred.
• A demonstrated commitment to quality and compliance, accompanied by a proven track record, is required. Outstanding interpersonal and leadership skills, as well as strong influence and relationship‑building capabilities with a focus on teamwork, are also necessary.

#LI-GSK

Skills

Biopharmaceuticals, Bioprocessing, Cell Line Development, Drug Development, Experimental Methods, Molecular Cell Biology, Pharmaceutical Industry, Pharmaceutical Manufacturing, Quality by Design, Regulatory Submissions, Simulation Models, Technical Writing, Technology Transfer

Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases - to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we're committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

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