Biopharmaceutical Production Manager

Scorpion Therapeutics; King of Prussia (PA); On-site; USD 180,000 - 240,000; Full time

Job summary

Scorpion Therapeutics is seeking a senior manufacturing leader to oversee 24/7 operations, manage production supervisors and frontline staff, and drive continuous improvement in biopharmaceutical manufacturing.

You will ensure compliance with GSK QMS/EHS and CFR/cGMP, develop workforce plans, set departmental priorities, and collaborate with engineering, validation, and tech transfer teams to meet safety, quality, and supply KPIs.

Qualifications

• Bachelor’s degree in a technical field and 7+ years in biopharma/manufacturing.
• 3+ years in a management role overseeing direct and indirect reports.
• Hands-on operations experience and prior people leadership.

Responsibilities

• Lead 24/7 manufacturing operations and production staff.
• Ensure compliance with GSK QMS/EHS, CFR/cGMP, OSHA.
• Oversee documentation practices and data integrity.
• Set priorities and meet safety, quality, and supply KPIs.
• Collaborate with engineering, validation, and tech transfer teams.

Skills

Biopharmaceuticals

Bioprocessing

Cell Line Development

Drug Development

Experimental Methods

Molecular Cell Biology

Pharmaceutical Industry

Pharmaceutical Manufacturing

Quality by Design

Regulatory Submissions

Simulation Models

Technical Writing

Technology Transfer

Education

Bachelor’s degree in Chemical, Mechanical, Biomedical, Engineering, or Biotechnology

Job description

Responsibilities:

• Carry out tasks aligned with core values: Accountability for Impact, Ambition for Patients, Doing the Right Thing.
• Follow leadership expectations: set priorities, motivate others, and support team growth.
• Partner with NPI leads and support team managers to implement new products and equipment.
• Manage 4 shift operations in a 24/7 facility, overseeing production supervisors, specialists, and front-line staff.
• Ensure compliance with manufacturing, safety, and environmental regulations (GSK QMS/EHS, CFR/cGMP, OSHA, and local/state/federal requirements).
• Oversee documentation practices: approve Batch Documents; ensure SOPs and logbooks are maintained within compliance; ensure data integrity controls.
• Set departmental priorities using operational data and staff capacity.
• Meet KPIs for safety, quality, and supply.
• Approve safety and compliance investigations; promote transparency and a values-driven culture.
• Hold teams accountable for cross-functional work (engineering, validation, tech transfer studies).
• Recommend updates to digital platforms.
• Develop workforce plans for staff development and performance management.
• Define production and staffing requirements to meet schedules.

Qualifications:

• Bachelor’s degree in Chemical, Mechanical, Biomedical, Engineering, or Biotechnology.
• 7+ years’ experience in biopharmaceutical, biotechnology, or related technology-driven industry.
• 3+ years in a management role overseeing direct and indirect reports.

Preferred Qualifications:

• Master’s degree in biological sciences or engineering.
• 5+ years’ experience in large-scale manufacturing.
• Proficient verbal and written communication; strong team collaboration.
• Hands-on operations experience and prior people leadership.
• Demonstrated commitment to quality and compliance; strong interpersonal and leadership skills.

Skills:

• Biopharmaceuticals, Bioprocessing, Cell Line Development, Drug Development, Experimental Methods, Molecular Cell Biology, Pharmaceutical Industry, Pharmaceutical Manufacturing, Quality by Design, Regulatory Submissions, Simulation Models, Technical Writing, Technology Transfer