Biomedical Engineer

BuzzClan; Milwaukee (WI); On-site; USD 90,000 - 150,000; Full time

Job summary

BuzzClan seeks a hands-on Biomedical Engineer/Scientist to drive formulation development and plate-based workflows for drug discovery. The role focuses on dry and liquid biochemical products across tablets, sachets, vials, and HTS plates, with emphasis on scale-up and technology transfer.

The candidate will design and validate formulations, manage analytical testing, and support pilot manufacturing readiness. A MS/PhD and multi-disciplinary expertise are preferred for this position.

Qualifications

• MS or PhD in Biomedical Engineering or related field.
• Hands-on experience with two or more listed formulations or processes.
• Experience with scale-up and technology transfer.
• Ability to document studies and develop prototypes.

Responsibilities

• Develop and optimize dry and liquid formulations, biochemical reagents, buffers, excipients, and screening materials.
• Develop tablet, mini-tablet, sachet, vial, and HTS plate products.
• Operate/support tablet presses, powder blenders, solid/liquid dispensers, and plate-handling equipment.
• Develop dispensing workflows for 24-, 48-, 96-, and 384-well plates.
• Evaluate powder flow, blend uniformity, tablet properties, dosing accuracy, reconstitution, and plate uniformity.
• Perform analytical and stability testing using HPLC/UPLC, LC-MS, UV-Vis, Karl Fischer, pH, conductivity, and dissolution.
• Troubleshoot formulation, tableting, dispensing, evaporation, precipitation, and cross-contamination issues.
• Develop specifications, batch records, protocols, plate maps, and technical documentation.
• Support scale-up, technology transfer, packaging, and pilot manufacturing readiness.

Skills

Dry formulation

Tableting

Powder processing

Automated dispensing

HTS plate preparation

Education

MS or PhD in Biomedical Engineering or related field

Tools

HPLC/UPLC

LC-MS

Karl Fischer

pH meter

UV-Vis

Job description

Schedule: Monday–Friday, 8:00 AM–5:00 PM

Location: Milwaukee WI 53209 USA

Position Overview

We are seeking a hands‑on Biomedical Engineer Scientist / Scientist / Engineer with experience in formulation development, biochemical products, powder processing, tableting, automated dispensing, and HTS plate preparation.

The role will focus on developing and scaling dry and liquid biochemical products in formats including tablets, sachets, vials, and 24-, 48-, 96-, and 384‑well plates for drug discovery and development workflows.

Key Responsibilities

• Develop and optimize dry and liquid formulations, biochemical reagents, buffers, excipients, and screening materials.
• Develop tablet, mini‑tablet, sachet, vial, and HTS plate products.
• Operate/support tablet presses, powder blenders, solid/liquid dispensers, and plate‑handling equipment.
• Develop dispensing workflows for 24-, 48-, 96-, and 384‑well plates.
• Evaluate powder flow, blend uniformity, tablet properties, dosing accuracy, reconstitution, and plate uniformity.
• Perform analytical and stability testing using HPLC/UPLC, LC-MS, UV‑Vis, Karl Fischer, pH, conductivity, and dissolution techniques.
• Troubleshoot formulation, tableting, dispensing, evaporation, precipitation, and cross‑contamination issues.
• Develop specifications, batch records, protocols, plate maps, and technical documentation.
• Support scale‑up, technology transfer, packaging, and pilot manufacturing readiness.

Required Qualifications

• MS or PhD in Biomedical Engineering, Biochemical Engineering, Pharmaceutical Sciences, Pharmaceutics, Chemical Engineering, Biochemistry, Chemistry, Materials Science, or a related field.
• Hands‑on experience in at least two of the following:
• Dry formulation
• Tableting
• Powder processing
• Automated dispensing
• HTS plate preparation
• Experience with 24-, 48-, 96-, or 384‑well plate workflows.
• Strong knowledge of formulation stability, powder properties, excipients, solvent compatibility, and moisture sensitivity.
• Experience designing and documenting formulation, analytical, process‑development, or stability studies.
• Ability to independently develop prototypes and translate them into scalable processes.

Preferred Qualifications

• Experience with pharmaceutical/biochemical formulations, dry‑plated compounds, DMSO solutions, or chemical libraries.
• Experience with laboratory automation, robotics, low‑volume dispensing, or plate‑sealing systems.
• Knowledge of HPLC/UPLC, LC-MS, Karl Fischer, dissolution, LIMS, or plate‑data management.
• Experience with DoE, QbD, scale‑up, technology transfer, GLP/GMP, or ICH stability principles.

Ideal Candidate:

A hands‑on scientist or engineer with strong formulation + tableting/powder processing + automated dispensing/HTS experience who can take products from development through testing and pilot readiness.