Biomarker Program Lead for Clinical Trials

Treeline; Watertown (MA); On-site; USD 187,200 - 200,000; Full time

Job summary

Treeline Biosciences in Watertown, MA is seeking a Biomarker Lead to drive biomarker planning and execution across early and late clinical programs, design biomarker plans, identify labs/CROs, and supervise assay transfer and data QC.

Candidates should hold a PhD with postdoc training and 4–5 years of biotech/pharma biomarker experience; expertise in assay transfer, validation, and platforms (flow cytometry, IHC, NGS). Oncology experience is highly preferred.

Qualifications

• PhD with postdoctoral training in life sciences or related field.
• 4–5 years of industry biomarker experience in biotech/pharma.
• Expertise in assay transfer, validation and CRO oversight.
• Knowledge of biomarker platforms (flow cytometry, IHC, NGS, proteomics).
• Strong leadership, organization and cross-functional communication.
• Oncology experience preferred; CDx development is a plus.

Responsibilities

• Develop and oversee biomarker plans for each clinical protocol.
• Identify and qualify bioassay labs/CROs for biomarker assays.
• Lead assay transfer from Translational biology to labs/CROs.
• Oversee testing at labs/CROs ensuring QC and protocol adherence.
• Collaborate with Clinical Development, Data Management, Biostatistics, and Regulatory.
• Provide updates on biomarkers to internal stakeholders.
• Analyze biomarker data with translational and clinical teams.

Skills

Cross-functional leadership

Communication

Project management

Biomarker data analysis

Biomarker platforms

Education

PhD in Life Sciences (or related field)

Postdoctoral training

Tools

Flow cytometry

IHC

NGS

Proteomics

Assay transfer & CRO oversight

Job description

Treeline Biosciences in Watertown, MA is seeking a Biomarker Lead to drive biomarker planning and execution across early and late clinical programs, design biomarker plans, identify labs/CROs, and supervise assay transfer and data QC.

Candidates should hold a PhD with postdoc training and 4–5 years of biotech/pharma biomarker experience; expertise in assay transfer, validation, and platforms (flow cytometry, IHC, NGS). Oncology experience is highly preferred.