Biological Sciences Research Associate — CRISPR & Confocal Imaging

University of Delaware; Newark (DE); On-site; USD 52,000 - 78,000; Full time

Job summary

University of Delaware in Newark, DE is seeking a Research Associate II in Biological Sciences to participate in studies on mechanisms regulating extracellular vesicle shedding and uptake in neurons using C. elegans.

You will conduct imaging, genetics, and cell biology experiments, maintain notebooks, and analyze data to generate publication-ready figures. The role requires designing experiments, developing protocols, and collaborating with graduate and undergraduate students, with a focus on

Qualifications

• Bachelor’s degree in Biological Sciences or related field with 2+ years of related experience.
• Experience in independent research using cellular and molecular biology techniques.
• Proficiency with Microsoft Office; plasmid design, DNA sequencing and image analysis software.
• Experience with confocal microscopy preferred.
• Knowledge of lab facilities/equipment maintenance.
• Background in genetics.
• Strong organizational and oral communication skills.
• Ability to follow safety procedures and design/coordinate research protocols.
• Ability to work with diverse teams and individuals.

Responsibilities

• Plan and conduct C. elegans experiments requiring genetics understanding and data analysis.
• Operate light and fluorescence microscopes, centrifuges, pH meters, balances, spectrophotometers, gel documentation systems.
• Perform live animal confocal imaging and analyze images with Imaris and ImageJ.
• Design and create new C. elegans strains using CRISPR/Cas9 genome editing.
• Carry out molecular biology and biochemical techniques including PCR, qRT-PCR, Western blotting, and co-immunoprecipitation.
• Review primary literature to guide experiments and interpret results.
• Present results to lab group and plan future work.
• Collaborate with graduate and undergraduate students in the lab.
• Maintain safety and proper handling of hazardous materials; uphold EH&S standards.
• Manage strain and primer databases, monitor inventory, and order supplies.

Skills

Organizational skills and oral comms

Interpersonal skills

Genetics knowledge

Imaging software (ImageJ, Imaris)

Education

Bachelor’s degree in Biological Sciences

Tools

Imaris

ImageJ

CRISPR/Cas9 genome editing

Microsoft Office

DNA sequencing

Job description

University of Delaware in Newark, DE is seeking a Research Associate II in Biological Sciences to participate in studies on mechanisms regulating extracellular vesicle shedding and uptake in neurons using C. elegans.

You will conduct imaging, genetics, and cell biology experiments, maintain notebooks, and analyze data to generate publication-ready figures. The role requires designing experiments, developing protocols, and collaborating with graduate and undergraduate students, with a focus on