Bioinformatics Pipeline QA Engineer – NGS & Variant Calling

Vytwo; Prosper (TX); On-site; USD 110,000 - 150,000; Full time

Job summary

Vytwo in San Diego, CA is seeking a Bioinformatics Test Engineer to validate NGS data pipelines and workflows. You will bridge bioinformatics expertise with QA and automation to ensure data quality and reliability.

The role emphasizes testing strategies for alignment, variant calling, and annotation, with Python scripting and CI/CD workflows. Collaboration across teams and exposure to cloud environments are expected.

Qualifications

• Must have bioinformatics experience in testing or QA.
• Strong Python scripting and data validation skills.
• Hands-on with Git, CI/CD and cloud workflows.

Responsibilities

• Design and execute testing strategies for NGS pipelines (alignment, variant calling).
• Perform data validation, regression testing, and discrepancy analysis.
• Develop automated test scripts (Python).
• Translate requirements into test cases and validation criteria.
• Work with CI/CD pipelines and cloud-based workflows.
• Collaborate with cross-functional teams to ensure data accuracy and reliability.

Skills

Bioinformatics

Genomics

NGS workflows

Python scripting

Testing mindset

Data validation

Communication

Problem solving

Tools

Git

CI/CD pipelines

Nextflow

Snakemake

Cloud platforms

Job description

Vytwo in San Diego, CA is seeking a Bioinformatics Test Engineer to validate NGS data pipelines and workflows. You will bridge bioinformatics expertise with QA and automation to ensure data quality and reliability.

The role emphasizes testing strategies for alignment, variant calling, and annotation, with Python scripting and CI/CD workflows. Collaboration across teams and exposure to cloud environments are expected.