Bioinformatician II

Duke Clinical Research Institute; Durham (NC); On-site; USD 90,000 - 120,000; Full time

Benefits offered by this job

Health insurance

Paid time off

Tuition assistance for employees and 4

Job summary

Duke Clinical Research Institute in Durham, NC, seeks a Bioinformatician II to support multidisciplinary research at the intersection of virology, immunology, and exposure biology.

Design, implement, and maintain workflows and databases for multi-omic data; contribute to single-cell RNA-seq and spatial transcriptomics analyses; collaborate with researchers and provide bioinformatics training.

Qualifications

• PhD in Bioinformatics, Computational Biology, or a related field (or MS with substantial relevant experience).
• Strong programming skills (e.g., R, Python, or equivalent).
• Experience in building, maintaining, and working with databases (SQL).
• Experience analyzing genomic data.

Responsibilities

• Design, create, and enhance workflows, databases, front-end interfaces, and other computing tools for tracking, moving, distribution, sharing, integration, and analysis of a variety of multi-omic, phenotypic, clinical and experimental data.
• Contribute to the analysis of single-cell RNA-seq, spatial transcriptomics, and multi-omic datasets.
• Apply computational and machine learning approaches to build mechanistic biological models and rationally design therapeutics.
• Identify solutions and investigate and learn new approaches necessary to adapt existing or new workflows.
• Collaborate with teams of researchers and scientists providing bioinformatics training, consulting, application support and development.

Skills

Programming (R/Python)

Genomic data analysis

Communication

Education

PhD in Bioinformatics or related field

MS with substantial relevant experience

Tools

SQL

Job description

School of Medicine Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more than 6,200 staff, the Duke University School of Medicine along with the Duke University School of Nursing, and Duke University Health System comprise Duke Health, a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Health Integrated Practice, Duke Primary Care, Duke Home Care and Hospice, Duke Health and Wellness, and multiple affiliations.

Be You.

The Heaton Laboratory (https://heaton.labs.duke.edu/), a member of the Duke Center for Virology (https://sites.duke.edu/dukevirology/), is seeking a highly motivated Bioinformatician II to support multidisciplinary research at the intersection of virology, immunology, cell biology, and exposure biology.

Minimum Requirements

• PhD in Bioinformatics, Computational Biology, or a related field (or MS with substantial relevant experience)
• Strong programming skills (e.g., R, Python, or equivalent)
• Experience in building, maintaining, and working with databases (SQL)
• Experience analyzing genomic data

Preferred Qualifications

• Experience integrating high-dimensional datasets (e.g. exposure status, next-generation sequencing, experimental data) to identify outcome-associated signatures
• Experience applying computational and machine learning approaches to biological data
• Strong communication skills and ability to collaborate in a team-oriented environment

Be Bold.

About the Position:

• Design, create, and enhance workflows, databases, front-end interfaces, and other computing tools for tracking, moving, distribution, sharing, integration, and analysis of a variety of multi-omic, phenotypic, clinical and experimental data
• Contribute to the analysis of single-cell RNA-seq, spatial transcriptomics, and multi-omic datasets
• Apply computational and machine learning approaches to build mechanistic biological models and rationally design therapeutics
• Identify solutions and investigate and learn new approaches necessary to adapt existing or new workflows
• Collaborate with teams of researchers and scientists providing bioinformatics training, consulting, application support and development

Choose Duke.

• Work on cutting-edge questions in virology and immunology with direct relevance to therapeutic development and understandings of disease pathology, susceptibility, and transmission
• Access to rich, multi-modal datasets from state-of-the-art experimental systems and human studies
• Collaborative, interdisciplinary environment integrating computational and experimental approaches

Join our award-winning team as identified by Forbes magazine as America's Best Large Employer 2024 and be part of an inclusive culture that values excellence, innovation, and discovery. As an organization, we have exciting opportunities to be forward-thinking leaders in our field. We want talented individuals to join us, examine our current operations, and create innovative solutions that will revolutionize and enhance the way we approach our work.

Duke University is consistently ranked among the top universities worldwide and is renowned for its cutting-edge research across disciplines.

Beyond the engaging work, you'll also benefit from Duke's competitive benefits package including health insurance plans, generous paid time off, retirement programs with employer contributions, tuition assistance for employees and their children, and more.

Hiring Statements:

Duke is an Aff…? ...?

Anticipated Pay Range: Duke University provides an annual base salary range for this position as USD $0.00 to USD $0.00. Duke University considers factors such as (but not limited to) scope and responsibilities of the position; candidate's work experience, education/training, and key skills; internal peer equity; as well as market and organizational considerations when extending an offer.

Your total compensation goes beyond thedollars on your paycheck. Duke provides comprehensive and competitive medical and dental care programs, generous retirement benefits, and a wide array of family-friendly and cultural programs to eligible team members. Learn more at: https://hr.duke.edu/benefits/

Equal Opportunity Employer: Duke is an Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex (including pregnancy and pregnancy- related conditions), sexual orientation, or military status.

Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas-an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.

Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities. Additional information and reasonable accommodation(s) can be requested with Duke Access and Accommodations Services (email: [e-mail]; phone: [phone]).