Basic Scientist - Assistant, Associate or Full In Residence Professor

UCSF Health, AG; San Francisco (CA); On-site; USD 150,000 - 350,000; Full time

Job summary

Gladstone-UCSF Institute of Genomic Immunology and UCSF Department of Neurological Surgery seek a faculty member at the Assistant, Associate, or Full Professor level to lead a brain tumor immunotherapy program.

The successful candidate will be based at Gladstone Institutes (Mission Bay) with a primary UCSF appointment and an Investigator affiliation at the Institute, focusing on pioneering genomic immunology approaches.

Qualifications

• Ph.D., M.D./Ph.D., or equivalent degrees.
• Independent basic science research program in genomic immunology or immunotherapy for brain tumors.
• Strong background in immunology, genomics, genetics, genome engineering, and/or synthetic biology with meaningful achievements.

Responsibilities

• Develop extramurally funded research programs and mentor graduate and medical students.
• Hold primary faculty appointment at UCSF Department of Neurological Surgery and Investigator affiliation at Gladstone-UCSF Institute of Genomic Immunology.
• Lead a new brain tumor immunotherapy research program including preclinical models and clinical translation.

Skills

Genomics immunology

Immunology

Genome engineering

Synthetic biology

Immunotherapy

Education

Ph.D., M.D./Ph.D., or equivalent

Tools

CRISPR

Job description

Application Window

Open date: October 19, 2026

Next review date: Wednesday, Nov 18, 2026 at 11:59pm (Pacific Time)

Final date: Wednesday, Apr 19, 2028 at 11:59pm (Pacific Time)

Position Description

The UCSF Department of Neurological Surgery and The Gladstone-UCSF Institute of Genomic Immunology are jointly recruiting a faculty member at the Assistant, Associate or Full Professor level to lead a new research program supported in part by the UCSF Brain Tumor Center, focused on immunotherapy for brain tumors. The successful candidate will be a basic scientist based at the Gladstone Institutes (Mission Bay), with primary faculty appointment in the Department of Neurological Surgery. Candidates must have a strong background in immunology, genomics, genetics, genome engineering, and/or synthetic biology, and significant achievements and meaningful promise in developing novel immunotherapies for brain tumors. We invite applications from scientists with Ph.D., M.D./Ph.D., or equivalent degrees who are establishing or have established an independent basic science research program in brain tumor immunotherapy research.

Relevant areas of research include, but are not limited to:

• Genome engineering to enhance adoptive cellular therapies for brain cancer
• Protein design and engineering in the context of the immune system and immunotherapies for brain cancer
• Systems immunology and immunotherapy in neuro-oncology
• Preclinical disease models and clinical translation of innovative immunotherapies in the context of the brain

Investigators will be expected to develop extramurally sponsored research programs and educate, mentor, and develop graduate and medical students. The successful candidate will hold a primary faculty appointment in the UCSF Department of Neurological Surgery, along with an Investigator affiliation at the Gladstone-UCSF Institute of Genomic Immunology, as an Assistant, Associate or Full Professor, and will be assigned dedicated research space, primarily located in new Gladstone Institutes space at Mission Bay, with additional support from the UCSF Brain Tumor Center.

About Gladstone-UCSF Institute of Genomic Immunology

To harness the immense potential offered by immunotherapies, the Gladstone-UCSF Institute of Genomic Immunology combines emerging biomedical technologies at the intersection of human immunology, genomics, CRISPR genome engineering, computational biology, and synthetic biology.

The institute's scientists deepen knowledge of how DNA sequences control cell functions in the human immune system. Their discoveries will enable the next generation of immunotherapies for cancer, autoimmune diseases, infectious diseases, inflammation and beyond.

This institute is the result of a close partnership between Gladstone Institutes and the University of California, San Francisco (UCSF). With wet and dry lab space to be housed (starting in 2027) in a new building on the Mission Bay campus, it creates a unified community across the two campuses and combines UCSF's world-class immunology and planned cell therapy efforts with Gladstone's expertise in the host-pathogen interface, iPS cells, computational biology, and CRISPR gene editing technologies.

About UCSF

UC San Francisco is the leading university dedicated to advancing health worldwide through preeminent biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care. Within our overarching advancing health worldwide mission, UCSF is devoted at every level to serving the public.

Required Qualifications

• Ph.D., M.D./Ph.D., or equivalent degrees
• Candidates must be establishing, or have established, an independent basic science research program in genomic immunology or immunotherapy for brain tumors. Relevant areas of research include, but are not limited to:
  • Genome engineering to enhance adoptive cellular therapies for brain cancer
  • Protein design and engineering in the context of the immune system and immunotherapies for brain cancer
  • Systems immunology and immunotherapy in neuro-oncology
  • Preclinical disease models and clinical translation of innovative immunotherapies in the context of the brain
• Strong background in immunology, genomics, genetics, genome engineering, and/or synthetic biology, and significant achievements and meaningful promise in their field.

Application Requirements

• Curriculum Vitae - CV must clearly list current and/or pending qualifications (e.g. board eligibility/certification, medical licensure, etc.).
• Cover Letter
• Statement of Research (2-4 pages)
• Statement of Teaching (1 page max)

Reference Requirements

• 3 reference contacts required

Additional Information

• Title and salary will be commensurate with education and experience.
• Gladstone is an equal opportunity employer.

The total compensation for this position ranges from $150,000-$350,000.

Total compensation at the University of California, San Francisco includes your base salary, which is determined by your rank and step at appointment, and negotiated pay for Health Sciences Compensation Plan members. Faculty who are members of the Health Sciences Compensation Plan may also be eligible for additional incentive pay.

Job location

San Francisco, CA

About UC San Francisco

As a University employee, you will be required to comply with all applicable University policies and/or collective bargaining agreements, as may be amended from time to time. Federal, state, or local government directives may impose additional requirements.

The University of California is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected status under state or federal law.

UCSF is committed to welcoming and serving all people, honoring the dignity of every individual without preference or prejudice, in support of its public mission and in alignment with our PRIDE values and Principles of Community.

As a condition of employment, the finalist will be required to disclose if they are subject to any final administrative or judicial decisions within the last seven years determining that they committed any misconduct.

• Misconduct means any violation of the policies or laws governing conduct at the applicant's previous place of employment, including, but not limited to, violations of policies or laws prohibiting sexual harassment, sexual assault, or other forms of harassment, or discrimination, as defined by the employer.
• UC Sexual Violence and Sexual Harassment Policy
• UC Anti-Discrimination Policy
• APM - 035: Affimative Action and Non discrimination in Employment