Associate Scientist, Small Scale Synthesis

ZipRecruiter; Madison (WI); On-site; USD 58,000 - 68,000; Full time

Job summary

A leading biopharmaceutical company is seeking an Associate Scientist for its Discovery Chemistry Department in Madison, WI. The role involves oligonucleotide synthesis and analytical chemistry, offering a dynamic environment focused on innovative drug development. The successful applicant will work alongside experienced scientists and contribute to significant research projects.

Benefits

Competitive salaries

Excellent benefits package

Qualifications

• B.S. in Chemistry or Biochemistry required.
• 0-2 years of chemistry laboratory experience.
• Familiarity with HPLC and organic/analytical techniques.

Responsibilities

• Synthesize, purify, and analyze oligonucleotides.
• Maintain laboratory documentation and track project timelines.
• Adhere to safe laboratory practices.

Skills

Analytical techniques

Organic chemistry

Analytical chemistry

Oligonucleotide synthesis

Education

B.S. in Chemistry

B.S. in Biochemistry

Tools

HPLC

Job description

Job Description

Arrowhead Pharmaceuticals, Inc. (Nasdaq: ARWR) is a clinical stage biopharmaceutical company that develops medicines to treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead's RNAi-based therapeutics leverage this natural pathway of gene silencing.

Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins involved with disease. The depth and versatility of our RNAi technologies enable us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.

Arrowhead's corporate headquarters is in Pasadena, CA, with research and development teams in Madison, WI, and San Diego, CA, and a state-of-the-art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators collaborating to bring new therapies to patients in need.

The Position

Arrowhead Pharmaceuticals is seeking an Associate Scientist to join the Discovery Chemistry Department. The successful candidate will primarily focus on oligonucleotide synthesis, purification, analytical chemistry, and contributing to specific program goals. The Associate Scientist will join a team of highly motivated and experienced scientists and will contribute to the success of Arrowhead programs.

Responsibilities

• Maintain a well-documented laboratory notebook
• Track progress against project timelines, generate regular status updates, and communicate progress and issues to management
• Manage time effectively to meet deadlines
• Adhere to safe laboratory practices
• Perform synthesis, purification, and analysis of oligonucleotides
• Assist with maintenance of bioconjugate and oligonucleotide inventory

Requirements

• B.S. in Chemistry or Biochemistry with excellent understanding of organic and analytical chemistry
• 0-2 years of experience working in a chemistry laboratory
• Experience with a wide range of analytical techniques, especially HPLC
• Ability to quickly learn new procedures and techniques

Preferred Experience

• Experience working with large molecule synthetic targets (especially oligonucleotides) in academic or industry settings
• Previous experience working in a pharmaceutical setting

Wisconsin pay range: $58,000—$68,000 USD

Arrowhead provides competitive salaries and an excellent benefits package.

All applicants must have authorization to work in the US for a company.

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