Associate Scientist, Product Sciences

Bristol-Myers Squibb Co; Seattle (WA); On-site; USD 88,000 - 107,000; Full time

Benefits offered by this job

Comprehensive benefits

Flexible Time Off

11 paid holidays

Vacation time

Stock opportunities

Job summary

Bristol Myers Squibb is seeking an Associate Scientist / Senior Research Associate to support CAR T cell product development in Seattle, WA. The role focuses on in vitro studies to build product and manufacturing process understanding, using human T cells and flow cytometry-based analyses to interrogate phenotype and function.

The successful candidate will perform characterization assays, analyze data, and collaborate with the Product Sciences Team.

Qualifications

• B.S. degree in immunology, cell biology or related field.
• Experience with human T cell biology and analytical tools for T cell phenotype and function.
• Experience with in vitro cell culture systems and sterility techniques.
• Experience with multi-parameter flow cytometry.
• Ability to work in a fast-paced team, meet deadlines and prioritize multiple projects.
• Strong attention to detail and excellent communication skills.

Responsibilities

• Optimize and execute CAR T cell characterization using flow cytometry and functional assays.
• Quantify secreted cytokines and perform molecular assays as needed.
• Conduct statistical analysis and present results after studies.
• Collaborate with the Product Sciences Team to identify analytical approaches.
• Assist with labs management tasks and inventory control.
• Document work thoroughly in electronic lab notebooks.

Skills

T cell biology

Flow cytometry

Cell culture

Data analysis

Attention to detail

Communication

Time management

Education

B.S. in immunology or related

Tools

Multi-parameter cytometry

Job description

At Bristol Myers Squibb, our employees often ask, “Who are you working for?”—a question that fuels collaboration, accountability, and urgency in our work. Our purpose-driven culture inspires us to discover, develop, and deliver innovative medicines to prevail over serious diseases. We offer uniquely interesting and meaningful work, opportunities for growth, and a supportive environment that values inclusion, wellbeing, flexibility, and comprehensive benefits. This is work that transforms the lives of patients, and the careers of those who do it.

The Cell Therapy Product Sciences department is seeking a Research Associate or Senior Research Associate to support the development of CAR T cell products. The goal of BMS Cell Therapy is to revolutionize medicine by re-directing the body’s immune cells to specifically target cancer cells. The Product Sciences Team is responsible for developing and executing characterization assays and mechanism of action studies to support the development of CAR T cell therapies. The primary focus of the Product Sciences Research Associate role will be to execute in vitro studies to build CAR T cell product and manufacturing process understanding. Successful candidates will have a solid foundation in human T cell biology and a proven track-record of implementation and optimization of vitro cell-based assays using human immune and/or tumor cells.

Job Description:

• Optimize and execute characterization of CAR T cells leveraging flow cytometry, cell-based functional immunoassays, quantification of secreted cytokines and molecular assays
• Perform statistical data analysis, where applicable
• Present experimental findings/results following study completion
• Collaborate with other members of the Product Sciences Team for the identification and prioritization of novel analytical approaches for interrogating CAR T cell phenotype and function.
• Assume some laboratory management responsibilities (i.e. maintaining general laboratory space organization, placing orders for general laboratory supplies, cell culture maintenance, cell and biological material inventory maintenance)
• Timely and thorough documentation and completion of electronic laboratory notebooks

Basic Qualifications:

• B.S. degree in immunology, cell biology or related field
• Experience with human T cell biology and analytical tools for interrogating T cell phenotype and function (e.g. cytotoxicity assays, proliferation, cytokine production assays, multi-color conventional and spectral flow cytometry)
• Experience with in vitro cell culture systems (i.e. maintaining cell lines and/or primary cells in culture, comfortable with sterility techniques)
• Experience with multi-parameter flow cytometry
• Proven ability to work in a high-paced team environment, meet deadlines, & prioritize work on multiple projects
• Strong detail orientation and excellent interpersonal, written and verbal communication skills
• Flexibility with work schedule to support the maintenance of cell cultures and execution of cell-based assays

Preferred Qualifications:

• Experience with in vitro T cell functional assays
• Experience with transduction/transfection protocols to generate CAR T cells
• Experience with standard and next generation analytical platforms for the characterization of T cell phenotype, differentiation, and function (transcriptome and secretome profiling, metabolic analysis, etc)
• Experience with data visualization software and/or coding-based data analysis (i.e.JMP, Prism, R or Python)
• Track record of successful internal and/or external scientific collaborations

We hire for skills and capabilities, not just credentials – if this role excites you, but doesn’t perfectly match your resume, we encourage you to apply anyway.

Compensation Overview:

Seattle - WA: $88,430 - $107,151

The starting pay range(s) listed above is for full-time employees (FTE). You may also be eligible for additional discretionary incentive cash and stock opportunities. We determine starting pay thoughtfully – carefully considering the nature of the role, required skills, work location, schedule and the knowledge and experience you bring. Final compensation is guided by pay equity principles and applicable employment laws. Compensation programs are reviewed on an ongoing basis and may be adjusted over time to reflect evolving market factors, and individual, team or Company performance.

Benefits:

Subject to the terms and conditions of the applicable plans then in effect, you may be eligible to participate in our comprehensive benefit plans – including wellbeing support, retirement and financial protection benefits, and insurance offerings (medical, dental, vision, life and disability).

U.S.-based exempt employees are eligible for Flexible Time Off (FTO), which provides paid time off without a set accrual limit, subject to manager approval, along with 11 paid company holidays each year.

Non-exempt employees, RayzeBio employees, and employees located in Puerto Rico receive 160 hours of paid vacation annually for new hires (subject to manager approval), 11 paid company holidays, and 3 optional holidays.

Depending on eligibility, employees may also have access to additional time-off benefits, including paid sick leave, up to two paid volunteer days per year, summer hours flexibility, and leaves of absence for medical, personal, parental, caregiver, bereavement, or military needs. Eligible employees also enjoy an annual Global Shutdown between Christmas Day and New Year's Day.

U.S.-based job seekers can explore full benefit offerings at https://careers.bms.com/benefits

How We Work

Where you work matters – because collaboration, innovation and patient impact happen in many settings. Our roles are structured across four work models: site-essential, site-by-design, field-based and remote-by-design. The model assigned to this role is based on its core responsibilities. Learn more at https://careers.bms.com/ways-of-working.

Supporting People with Disabilities

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to [e-mail]. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

Candidate Rights

BMS will consider qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

For roles based in Los Angeles County only: If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/

Data Protection

We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at https://careers.bms.com/fraud-protection.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

If this posting is missing required information required by local law or incorrect, contact BMS at [e-mail] the Job Title and Requisition number. Do not send application-related inquiries to this email. To check your application status, please login to your Candidate Home Account.

R1606267 : Associate Scientist, Product Sciences