Associate Scientist, Product Sciences

Bristol Myers Squibb; Seattle (WA); On-site; USD 88,000 - 107,000; Full time

Job summary

Bristol Myers Squibb is seeking a Research Associate or Senior Research Associate in Seattle to support CAR T cell product development within the Cell Therapy Product Sciences department. You will perform in vitro studies to build understanding of CAR T cell products and manufacturing processes, leveraging flow cytometry and immunoassays while ensuring meticulous documentation.

The role requires a strong background in human T cell biology, multi-parameter cytometry, and cell culture, with the

Qualifications

• B.S. degree in immunology, cell biology or related field
• Experience with human T cell biology and analytical tools for T cell phenotype and function
• Experience with in vitro cell culture systems
• Experience with multi-parameter flow cytometry
• Proven ability to work in a high-paced team environment, meet deadlines and prioritize multiple projects
• Strong detail orientation and interpersonal, written, verbal communication skills
• Flexibility with work schedule to maintain cell cultures and assays

Responsibilities

• Optimize and execute characterization of CAR T cells using flow cytometry and functional immunoassays
• Perform statistical data analysis where applicable
• Present experimental findings after study completion
• Collaborate with Product Sciences Team on novel analytical approaches
• Assist with laboratory management tasks and inventory
• Maintain electronic laboratory notebooks with thorough documentation

Skills

B.S. degree required

Immunology knowledge

T cell biology

Analytical data interpretation

Team collaboration

Documentation and record-keeping

Flexibility with schedule

Education

B.S. degree in immunology/cell biology

Tools

Flow cytometry

Spectral flow cytometry

Cytotoxicity assays

Proliferation assays

Cytokine assays

Cell culture

Job description

At Bristol Myers Squibb, our employees often ask, “Who are you working for?”—a question that fuels collaboration, accountability, and urgency in our work. Our purpose-driven culture inspires us to discover, develop, and deliver innovative medicines to prevail over serious diseases. We offer uniquely interesting and meaningful work, opportunities for growth, and a supportive environment that values inclusion, wellbeing, flexibility, and comprehensive benefits. This is work that transforms the lives of patients, and the careers of those who do it.

The Cell Therapy Product Sciences department is seeking a Research Associate or Senior Research Associate to support the development of CAR T cell products. The goal of BMS Cell Therapy is to revolutionize medicine by re-directing the body’s immune cells to specifically target cancer cells. The Product Sciences Team is responsible for developing and executing characterization assays and mechanism of action studies to support the development of CAR T cell therapies. The primary focus of the Product Sciences Research Associate role will be to execute in vitro studies to build CAR T cell product and manufacturing process understanding. Successful candidates will have a solid foundation in human T cell biology and a proven track‑record of implementation and optimization of vitro cell‑based assays using human immune and/or tumor cells.

Job Description

• Optimize and execute characterization of CAR T cells leveraging flow cytometry, cell-based functional immunoassays, quantification of secreted cytokines and molecular assays
• Perform statistical data analysis, where applicable
• Present experimental findings/results following study completion
• Collaborate with other members of the Product Sciences Team for the identification and prioritization of novel analytical approaches for interrogating CAR T cell phenotype and function.
• Assume some laboratory management responsibilities (i.e. maintaining general laboratory space organization, placing orders for general laboratory supplies, cell culture maintenance, cell and biological material inventory maintenance)
• Timely and thorough documentation and completion of electronic laboratory notebooks

Basic Qualifications

• B.S. degree in immunology, cell biology or related field
• Experience with human T cell biology and analytical tools for interrogating T cell phenotype and function (e.g. cytotoxicity assays, proliferation, cytokine production assays, multi-color conventional and spectral flow cytometry)
• Experience with in vitro cell culture systems (i.e. maintaining cell lines and/or primary cells in culture, comfortable with sterility techniques)
• Experience with multi-parameter flow cytometry
• Proven ability to work in a high-paced team environment, meet deadlines, & prioritize work on multiple projects
• Strong detail orientation and excellent interpersonal, written and verbal communication skills
• Flexibility with work schedule to support the maintenance of cell cultures and execution of cell-based assays

Preferred Qualifications

• Experience with in vitro T cell functional assays
• Experience with transduction/transfection protocols to generate CAR T cells
• Experience with standard and next generation analytical platforms for the characterization of T cell phenotype, differentiation, and function (transcriptome and secretome profiling, metabolic analysis, etc)
• Experience with data visualization software and/or coding-based data analysis (i.e.JMP, Prism, R or Python)
• Track record of successful internal and/or external scientific collaborations

Compensation Overview

Seattle - WA: $88,430 - $107,151

The starting pay range(s) listed above is for full-time employees (FTE). You may also be eligible for additional discretionary incentive cash and stock opportunities. We determine starting pay thoughtfully – carefully considering the nature of the role, required skills, work location, schedule and the knowledge and experience you bring. Final compensation is guided by pay equity principles and applicable employment laws. Compensation programs are reviewed on an ongoing basis and may be adjusted over time to reflect evolving market factors, and individual, team or Company performance.

Benefits

• Subject to the terms and conditions of the applicable plans then in effect, you may be eligible to participate in our comprehensive benefit plans – including wellbeing support, retirement and financial protection benefits, and insurance offerings (medical, dental, vision, life and disability).
• U.S.-based exempt employees are eligible for Flexible Time Off (FTO), which provides paid time off without a set accrual limit, subject to manager approval, along with 11 paid company holidays each year.
• Non-exempt employees, RayzeBio employees, and employees located in Puerto Rico receive 160 hours of paid vacation annually for new hires (subject to manager approval), 11 paid company holidays, and 3 optional holidays.
• Depending on eligibility, employees may also have access to additional time-off benefits, including paid sick leave, up to two paid volunteer days per year, summer hours flexibility, and leaves of absence for medical, personal, parental, caregiver, bereavement, or military needs.
• Eligible employees also enjoy an annual Global Shutdown between Christmas Day and New Year's Day.
• U.S.-based job seekers can explore full benefit offerings at https://careers.bms.com/benefits

How We Work

Where you work matters – because collaboration, innovation and patient impact happen in many settings. Our roles are structured across four work models: site-essential, site-by-design, field-based and remote-by-design. The model assigned to this role is based on its core responsibilities. Learn more at https://careers.bms.com/ways-of-working.

Supporting People With Disabilities

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to [e-mail]. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

Candidate Rights

BMS will consider qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

Data Protection

We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at https://careers.bms.com/fraud-protection.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

If this posting is missing required information required by local law or incorrect, contact BMS at [e-mail] the Job Title and Requisition number. Do not send application-related inquiries to this email. To check your application status, please login to your Candidate Home Account.

R1606267 : Associate Scientist, Product Sciences