Associate Scientist, Post Doc Fellow- Translational Neuroscience

HireLifeScience; West Point (PA); On-site; USD 82,000 - 92,000; Full time

Benefits offered by this job

Medical, dental, vision

401(k) retirement plan

Job summary

HireLifeScience is seeking a highly motivated Postdoctoral Fellow in Neuroscience to join our Discovery Biology team in the United States. The role focuses on neurodegenerative disease biology, preclinical and translational research, and collaboration across disciplines to advance CNS drug discovery.

The ideal candidate will design and execute in vivo studies, generate mechanistic disease insights, and communicate findings through presentations and publications while utilizing state-of-the-art

Qualifications

• Ph.D. in Neuroscience, Pharmacology, Biomedical Sciences or related discipline.
• Ph.D. expected by Spring 2027.

Responsibilities

• Design and conduct preclinical studies using rodent models of neurodegenerative diseases.
• Perform hands-on in vivo experiments including dosing and tissue collection.
• Apply biochemical and molecular techniques such as ELISA and immunoassays.
• Develop and utilize in vivo MRI methods to assess neuroinflammation and endpoints.
• Integrate multimodal datasets to uncover disease mechanisms and therapeutic responses.
• Present findings via internal talks, conferences, and publications.

Skills

Neurodegeneration

In vivo experimentation

Data analysis (Python/MATLAB)

GraphPad Prism

Education

Ph.D. in Neuroscience or related

Ph.D. expected by Spring 2027

Tools

MRI

ELISA

Meso Scale Discovery

Immunohistochemistry

Quanterix-based assays

Job description

Job Description

Postdoctoral Fellow, Translational Neuroscience

Position Overview

We are seeking a highly motivated and innovative Postdoctoral Fellow in Neuroscience to join our Discovery Biology team. This laboratory-based position offers an exciting opportunity to advance novel therapies for neurodegenerative diseases through cutting-edge preclinical and translational research. The successful candidate will have strong expertise in neurodegeneration, animal models, translational biomarkers, and in vivo neuroimaging. They will independently design and execute studies, generate mechanistic insights into disease biology, and collaborate across multidisciplinary teams to support CNS drug discovery programs. With access to state-of-the-art biology and neuroimaging technologies, the candidate will generate critical insights into disease pathology and therapeutic efficacy, helping to shape the future of how we understand, visualize, and ultimately treat certain neurodegenerative diseases. The ideal candidate is a highly independent scientist who enjoys working at the bench, excels in in vivo experimentation, and is passionate about advancing innovative therapies for neurodegenerative diseases.

Key Responsibilities

• Design and conduct preclinical studies using rodent models of neurodegenerative diseases.
• Perform hands-on in vivo experiments, including dosing, tissue collection, and downstream biomarker analyses.
• Apply biochemical and molecular techniques, including ELISA, Meso Scale Discovery, immunohistochemistry, and ultrasensitive biomarker assays.
• Develop and utilize in vivo MRI methods to evaluate neuroinflammation, blood-brain barrier integrity, and other translational endpoints.
• Integrate imaging, fluid biomarker, and pharmacological datasets to uncover disease mechanisms and therapeutic responses.
• Collaborate with scientists across neuroscience, translational imaging, pharmacology, and data science to generate scientific insights that influence project strategy and decision-making.
• Present findings through internal presentations, scientific conferences, and peer-reviewed publications.

Education Requirements

• Must currently hold a Ph.D. OR
• Receive a Ph.D. no later than spring 2027
• Ph.D. in Neuroscience, Pharmacology, Biomedical Sciences, or a related discipline.

Required Skills & Experience

• Expertise with rodent models of neurodegenerative disease.
• Strong hands-on experience with molecular and cellular biology techniques, such as ELISA, Meso Scale Discovery, immunohistochemistry, and/or Quanterix-based assays.
• Hands-on experience with MRI or other translational imaging approaches.
• Understanding of PK/PD principles and translational pharmacology.
• Proficiency in data analysis and visualization tools, such as GraphPad Prism, HALO, and image analysis using MATLAB and/or Python.
• Demonstrated ability to independently design, execute, and troubleshoot complex studies.
• Strong scientific communication skills, evidenced by publications and presentations.

Preferred Skills & Experience

• Experience with translational biomarkers and mechanism-based drug development.
• Experience with transcriptomics, proteomics, or multi-omics data generation and analysis.
• Research experience in Alzheimer's disease, Parkinson's disease, ALS, or related CNS disorders.
• Experience working in multidisciplinary drug discovery teams.
• Demonstrated ability to lead collaborative projects and coordinate activities across scientific functions.

Salary

The salary range for this role is: $82,000- $92,000

Annual Bonus and Long-Term Incentive

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

Benefits

We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days.

Required Skills

Biomarkers, Data Analysis, Design of Experiments (DOE), Disease Models, Immunoassays, In Vivo Models, Neurodegeneration, Neuroinflammation, Scientific Research, Statistical Analysis

US and Puerto Rico Residents Only

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities.

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit: EEOC Know Your Rights EEOC GINA Supplement

We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts

San Francisco Residents Only

We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only

We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance

Employee Status

Regular

Relocation

Domestic

VISA Sponsorship

Yes

Travel Requirements

10%

Flexible Work Arrangements

Not Applicable

Shift

Not Indicated

Valid Driving License

No

Hazardous Material(s)

N/A

Job Posting End Date

10/12/2026

A job posting is effective until 11:59:59PM on the day BEFORE -the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Requisition ID

R419328