Associate Scientist, Post Doc Fellow- Immunology Analytics

Biopharma Careers

Cambridge (MA)

On-site

USD 65,000 - 85,000

Full time

2 days ago
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Job summary

Biopharma Careers is seeking a highly motivated Postdoctoral Research Fellow to join a cross-functional translational research team focused on immune-mediated inflammatory diseases. The fellow will leverage large-scale single-cell and spatial transcriptomics datasets from human tissue cohorts to identify disease-driving cellular programs and biomarker hypotheses.

The role offers mentorship across computational biology, immunology, and translational medicine; opportunities to publish first-author

Responsibilities

  • Receive mentorship from experts across computational biology, immunology, translational medicine, and drug discovery.
  • Publish first-author manuscripts in leading scientific journals.
  • Present at major international scientific conferences.
  • Develop expertise in cutting-edge single-cell, spatial, and multi-omics technologies.
  • Build a strong interdisciplinary network across academia and industry.
  • Gain experience translating complex biological datasets into actionable therapeutic insights.

Job description

**Job Description****Postdoctoral Research Fellow, Single-Cell and Spatial Transcriptomics in Immune-Mediated Inflammatory Diseases**We are seeking a highly motivated Postdoctoral Research Fellow to join a cross-functional translational research team focused on understanding the cellular and tissue mechanisms underlying chronic immune-mediated inflammatory diseases. The successful candidate will leverage large-scale single-cell and spatial transcriptomics datasets from human tissue cohorts to identify disease-driving cellular programs, tissue microenvironments, and translational biomarkers.This position offers a unique opportunity to work at the interface of computational biology, immunology, spatial genomics, and translational medicine while contributing to high-impact research programs spanning multiple therapeutic areas. The project aims to transform emerging multi-omics datasets into biological insights, biomarker hypotheses, disease-mechanism models, and translational strategies relevant to immune-mediated inflammatory diseases, including hidradenitis suppurativa (HS) and related disorders.**Career Development Opportunities**The fellow will:Receive mentorship from experts across computational biology, immunology, translational medicine, and drug discovery.Publish first-author manuscripts in leading scientific journals.Present at major international scientific conferences.Develop expertise in cutting-edge single-cell, spatial, and multi-omics technologies.Build a strong interdisciplinary network across academia and industry.Gain experience translating complex biological datasets into actionable therapeutic insights.**Scientific Impact**The successful candidate will contribute to the development of comprehensive cellular and spatial atlases of chronic immune-mediated inflammatory diseases, generating insights into disease circuits, tissue microenvironments, biomarker biology, and translational mechanisms. The work is expected to result in multiple high-impact publications and presentations while providing foundational knowledge to support therapeutic discovery and development.This research will help advance our understanding of how cellular programs and tissue organization contribute to disease pathogenesis and therapeutic response, enabling more precise approaches to target discovery, biomarker identification, and patient stratification.**Research Objectives**The postdoctoral fellow will lead three interconnected research areas:**Build Cellular Atlases of Immune-Mediated Inflammatory Diseases**Develop comprehensive single-cell transcriptomic references from diseased and comparator tissues.Identify disease-associated immune, epithelial, stromal, and vascular cell states.
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