Associate Scientist - Mass Spec Production (LC-MS/MS)

Kcas, Llc; Kansas City (MO); On-site; USD 60,000 - 90,000; Full time

Benefits offered by this job

Stock ownership program

KCAS University

Volunteer time off

Job summary

KCAS Bio, a fast-growing contract research organization headquartered in Kansas City, is seeking an Associate Scientist for the Mass Spec Bioanalysis Production group. You will contribute to study activities from sample preparation through data generation, while developing data integrity and troubleshooting skills under guidance.

In this role you will work with LC-MS/MS and advanced sample preparation to support drug discovery, preclinical, and clinical studies, maintaining GLP documentation and

Qualifications

• Bachelor’s or master’s degree in chemistry, biochemistry, biology, or related field with 1–3 years laboratory experience.
• Experience in a GLP-regulated laboratory environment.
• Experience with bioanalytical sample preparation and quantitative LC-MS/MS.
• Knowledge of GLP documentation, data integrity, and sample handling.

Responsibilities

• Execute study activities including sample prep, extraction, and LC-MS/MS analysis with moderate supervision.
• Perform established bioanalytical methods in regulated studies.
• Process data and prepare summaries for review by senior staff.
• Troubleshoot routine issues and escalate complex challenges.
• Maintain documentation in compliance with protocols, SOPs, and GLP.

Skills

LC-MS/MS

Bioanalytical prep

GLP compliance

Data integrity

Education

Bachelor’s or Master’s degree in chemistry/biochemistry/biology

Tools

LC-MS/MS instruments

Chromatography theory

Job description

When you work as an Associate Scientist in the Mass Spec Bioanalysis Production group at KCAS, you get to further our mission by applying your knowledge in bioanalytical and scientific principles to support regulated study execution with increasing independence. You will contribute to study activities from sample preparation through data generation while continuing to build your ability to assess data integrity and troubleshoot with guidance.
Our Mass Spec Bioanalysis Development team uses LC-MS/MS (Liquid Chromatography–Tandem Mass Spectrometry) techniques and sophisticated sample preparation methods to meet bioanalytical needs for drug discovery, preclinical, and clinical studies, including the bioanalysis of drugs and metabolites, biomarkers, and active endogenous compounds in biological fluids and tissues.

In this role, we will rely on you to:

• Execute assigned study activities including sample preparation, extraction, and LC-MS/MS analysis with moderate supervision
• Perform established bioanalytical methods and procedures in support of regulated studies
• Perform data processing and prepare data summaries for review by senior scientific staff
• Troubleshoot routine sample preparation, assay, or instrumentation issues and elevate more complex challenges appropriately
• Maintain accurate and complete documentation in compliance with study protocols, SOPs & GLP regulatory requirements
• Ensure proper sample identification, handling, tracking, and chain of custody
• Support investigation and documentation of deviations or unexpected study results as needed
• Maintain laboratory and instrument readiness to support study execution and established timelines
• Communicate study progress, issues, and potential risks to senior staff
• Perform all aspects of the job in a way that supports company brand and supports company mission, vision, and values

To qualify specifically for this role, you will have:

• Bachelor’s or master’s degree in chemistry, Biochemistry, Biology, or related scientific field with 1–3 years of relevant laboratory experience
• Hands‑on experience working in a GLP‑regulated laboratory environment
• Experience with bioanalytical sample preparation and quantitative LC‑MS/MS techniques
• Working knowledge of chromatographic principles and mass spectrometry
• Experience executing established bioanalytical methods in support of regulated studies
• Working knowledge of GLP documentation, data integrity, and sample handling requirements
• Ability to troubleshoot routine technical issues and recognize when escalation is necessary
• Strong attention to detail and ability to work effectively within SOP‑driven and regulated workflows

(Please note this is a representative summary of responsibilities, not a comprehensive or exclusive list of the duties to be performed in any position. Employees must follow instructions and perform additional duties as requested.)

WHO YOU ARE

You will thrive at KCAS Bio if you enjoy a relational environment, are purpose‑and values‑driven, embrace constant development and supportive leadership, and enjoy being part of innovative work.

WHAT YOU’LL GET

Our benefits include, and extend beyond, the traditional package. At KCAS Bio, you will enjoy company sponsored events like food trucks, family days and spirit days.You will grow in your career with KCAS University.You will be able to connect with like‑minded employees to further KCAS Bio's approach to key areas such as wellness, inclusion, and community outreach.You will engage as an owner in our stock ownership program. You will have access to the latest technology. And you will be able to invest in the community with paid time off to volunteer.

Learn more about the Benefits at KCAS Bio

WHO WE ARE

We are a fast‑growing contract research organization (CRO) headquartered in Kansas City, pioneering the latest drug development in both human and animal health fields.Demand for our expertise is growing and so is our need for great people to work in nimble, empowered teams committed to one another’s growth. At KCAS Bio, we advance both great science AND great people.

Learn more about what it is like to work at KCAS Bio

KCAS Bio is proud to be an Equal Opportunity Employer. Among other things, we provide equal employment opportunities without regard to race, color, religion, national origin, ancestry, marital status, veteran status, age, disability, pregnancy, genetic information, sex, sexual orientation, gender identity, or any other legally protected category; we recruit qualified candidates without regard to citizenship status based on internal processes that enable us to hire the right candidates consistent with the appropriate U.S. Immigration framework; and (3) we work with and provide reasonable accommodations to individuals with disabilities and for sincerely held religious beliefs, observances, and practices. Anyone who needs reasonable accommodation may send an email to [e-mail] call 913-248-3000 (for TTY assistance call 711) and ask for Human Resources.

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