Associate Scientist - Inflammation Research

Takeda; Boston (MA); On-site; USD 104,000 - 163,000; Full time

Job summary

Takeda seeks an Associate Scientist to advance GIDDU programs through in vitro pharmacology and assay development. You will design, execute, interpret, and document studies using primary human immune cells to generate high-quality data aiding program decisions and development activities.

You will lead multi-parameter flow cytometry assay qualification and analysis, while collaborating with cross-functional teams to address challenges and ensure robust scientific progress.

Qualifications

• Bachelor’s degree with 8+ years of relevant experience or Master’s with 4+ years.
• Hands-on experience designing and executing in vitro assays using primary human immune cells.
• Experience executing and analyzing multi-parameter flow cytometry assays, including panel design, staining, acquisition, compensation, gating, troubleshooting, and analysis.
• Experience generating reproducible pharmacology data and clearly documenting experimental results.
• Strong scientific writing skills, including preparation of study summaries, technical reports, figures, and presentations.
• Experience supporting development-stage studies or pharmacology data packages; experience with antibody-based therapeutics, CD38 biology, B cell or plasma cell biology, or immune-mediated disease pharmacology is preferred.
• Experience with target engagement, receptor occupancy, immune cell depletion, cytokine, proliferation, or viability assays, along with familiarity with assay qualification, reproducibility standards, and data documentation practices.

Responsibilities

• Lead the design, optimization, execution, and interpretation of in vitro pharmacology assays supporting GIDDU programs.
• Design and perform experiments using primary human immune cells, including culture, stimulation, treatment, phenotyping, and functional readouts.
• Support the development, troubleshooting, qualification, and analysis of multi-parameter flow cytometry assays to evaluate mechanism of action, target engagement, and immune cell phenotypes.
• Generate reproducible, high-quality data to support program decisions and development-stage activities.
• Contribute to study design, protocol execution, data analysis, and preparation of study reports.
• Maintain accurate, complete, and inspection-ready experimental records aligned with data integrity expectations.
• Prepare technical summaries, figures, reports, and presentations that clearly communicate data, limitations, and conclusions.
• Partner with internal research, translational, biologics, regulatory, and project teams to ensure studies meet program needs.
• Identify technical challenges, troubleshoot assays, and propose practical solutions to maintain study progress.
• Contribute to project team discussions and support scientific decision-making.

Skills

In vitro pharmacology

Flow cytometry

Primary human cells

Data interpretation

Study design

Documentation

Scientific communication

Cross-functional collaboration

Troubleshooting assays

Education

Bachelor’s degree in Immunology, Cell Biology, Molecular Biology, Biotechnology, Pharmacology

Master’s degree in related field

Tools

Flow cytometer

Panel design

Staining/Acquisition/Compensation

Gating/Analysis

Job description

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Job Description

Job Title: Associate Scientist

Location: Boston / Cambridge, MA

About the role:

The Associate Scientist will support the advancement of GIDDU programs through in vitro pharmacology and assay development. In this role, you will design, execute, interpret, and document studies using primary human immune cells to generate high-quality, reproducible data that supports program decisions and development-stage activities. You will bring hands-on expertise in multi-parameter flow cytometry, primary cell culture, and in vitro pharmacology assays while collaborating with cross-functional research and development teams to address technical challenges and advance scientific programs.

How you will contribute:

• Lead the design, optimization, execution, and interpretation of in vitro pharmacology assays supporting GIDDU programs.
• Design and perform experiments using primary human immune cells, including culture, stimulation, treatment, phenotyping, and functional readouts.
• Support the development, troubleshooting, qualification, and analysis of multi-parameter flow cytometry assays to evaluate mechanism of action, target engagement, and immune cell phenotypes.
• Generate reproducible, high-quality data to support program decisions and development-stage activities.
• Contribute to study design, protocol execution, data analysis, and preparation of study reports.
• Maintain accurate, complete, and inspection-ready experimental records aligned with data integrity expectations.
• Prepare technical summaries, figures, reports, and presentations that clearly communicate data, limitations, and conclusions.
• Partner with internal research, translational, biologics, regulatory, and project teams to ensure studies meet program needs.
• Identify technical challenges, troubleshoot assays, and propose practical solutions to maintain study progress.
• Contribute to project team discussions and support scientific decision-making.

What you bring to Takeda:

• Bachelor’s degree in Immunology, Cell Biology, Molecular Biology, Biotechnology, Pharmacology, or a related discipline with 8+ years of relevant experience, or a Master’s degree with 4+ years of relevant experience.
• Hands-on experience designing and executing in vitro assays using primary human immune cells.
• Experience executing and analyzing multi-parameter flow cytometry assays, including panel design, staining, acquisition, compensation, gating, troubleshooting, and analysis.
• Experience generating reproducible pharmacology data and clearly documenting experimental results.
• Strong scientific writing skills, including preparation of study summaries, technical reports, figures, and presentations.
• Experience supporting development-stage studies or pharmacology data packages; experience with antibody-based therapeutics, CD38 biology, B cell or plasma cell biology, or immune-mediated disease pharmacology is preferred.
• Experience with target engagement, receptor occupancy, immune cell depletion, cytokine, proliferation, or viability assays, along with familiarity with assay qualification, reproducibility standards, and data documentation practices.

More about us:

At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.

Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.

#GMSGQ #ZR1 #LI-MA1

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location:

Boston, MA

U.S. Base Salary Range:

$103,500.00 - $162,690.00

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

For information about our benefits, please click here.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

Boston, MA

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time

Job ExemptYesIt is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.