Associate Scientist, In vivo Pharmacology, Inflammation

Amgen Inc. (IR); Thousand Oaks (CA); On-site; USD 101,771 - 120,313; Full time

Benefits offered by this job

Competitive salary

Employee benefits package

Flexible work models

Annual bonus program

Job summary

A leading biotechnology company located in Thousand Oaks, CA, is looking for an Associate Scientist in In vivo Pharmacology. This role involves conducting in vivo studies, supporting preclinical disease models, and collaborating with scientists. Qualified candidates should have relevant degrees in Immunology or related fields, strong hands-on experience, and good organizational skills. The role requires flexibility for weekend or evening work as part of a dynamic team focused on delivering innovative treatments to patients.

Qualifications

• Master’s degree and 1 year of experience in Immunology or related field.
• Bachelor’s degree and 3 years of related experience.
• Strong understanding of Immunology and Inflammation biology.

Responsibilities

• Perform hands-on in vivo work with animal models.
• Support studies, collect samples, and communicate results.
• Participate in weekend/evening dosing rotations as needed.

Skills

Immunology

In vivo techniques

Data analysis

Communication skills

Education

Master’s degree in Immunology or related field

Bachelor’s degree in Immunology or related field

Tools

GraphPad Prism

Excel

PowerPoint

Word

Job description

Associate Scientist, In vivo Pharmacology, Inflammation page is loaded## Associate Scientist, In vivo Pharmacology, Inflammationremote type: On Sitelocations: US - California - Thousand Oakstime type: Full timeposted on: Posted Todayjob requisition id: R-241004## **Career Category**Scientific## ## **Job Description**## Join Amgen’s Mission of Serving PatientsAt Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.## Associate Scientist, In vivo Pharmacology, Inflammation## **What you will do**Let’s do this. Let’s change the world. In this vital role you will work in a highly dynamic in vivo pharmacology team executing in vivo preclinical disease models and in vitro assays in the vivarium and lab supporting pipeline programs.Key Responsibilities:* Perform hands-on in vivo work primarily mice, possibly rats in the vivarium daily.* Provide technical support for studies, dosing, sample/tissue collection, health checks, study setup and take down.* Work side-by-side with Scientists/Senior Scientists to execute and help design experiments.* Run concurrent studies, stay organized and detail-oriented to meet study timelines* Participate in weekend/evening dosing rotations as needed* Support in vitro assays as required* Communicate results to immediate team and follow established protocols and safety procedures* Work in a flexible team-oriented environment. Weekend and evening work may be required.## **What we expect of you**We are all different, yet we all use our unique contributions to serve patients. The Associate Scientist we seek is a driven, pro-active, independent, and enthusiastic scientist who wants to contribute to cutting edge science and serve patients in a highly productive team environment with these qualifications.**Basic Qualifications:**Master’s degree and 1 year of Immunology or related experienceORBachelor’s degree and 3 years of Immunology or related experience**Preferred Qualifications:*** M.S. degree in Immunology or related disciplines, or B.S. degree with commensurate scientific / drug discovery experience and track record of scientific excellence and productivity.* Strong understanding of Immunology and Inflammation biology and principles.* Willingness and curiosity to learn and explore new areas of research.* Significant experience designing and executing concurrent *in vivo* preclinical inflammation and autoimmune disease models. Experience with colitis (DSS, CD45RBhi T cell transfer, IL-10 KO), lupus (NZB/W, MRL-lpr, Imiquimod), and arthritis (CIA, CAIA), GvHD models preferred. Experience in Asthma, COPD, HS, PBC a plus.* Hands-on experience with in vivo techniques including dosing route of administration (i.v., i.p., p.o., i.n., i.t., r.o., i.d., s.c.), bleeds (r.o., cheek, tail), necropsy (organ collection (intestine/colon, lung, lymphnodes, spleen, liver, kidney, skin), cardiac bleed, lung BAL collection).* Hands-on experience in cellular, biochemical, histological, and molecular biology assay techniques (i.e. ELISA, MSD, quantitative RT-PCR, BCA protein measurements) preferred. Hands-on experience with multicolor flow cytometry including Spectral flow approaches and Immune cell populations is essential.* Computer literacy, especially proficiency with GraphPad Prism, Excel, PowerPoint and Word.* Attention to detail, excellent organizational and communication skills, accurate & timely record keeping and data analysis are essential.* Demonstrated track record of independent critical thinking and scientific achievement.* Demonstrated experience in pharmacology and *in vivo* models of inflammation/Immunology.## ## **What you can expect of us**As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:* A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts* A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan* Stock-based long-term incentives* Award-winning time-off plans* Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.## Apply now and make a lasting impact with the Amgen team.## **careers.amgen.com**In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.## Application deadlineAmgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.## SponsorshipSponsorship for this role is not guaranteed.As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation..**Salary Range**101,771.00 USD - 120,313.00 USD