Associate Scientist II/Scientist I, Predictive Stability

AbbVie Inc.; Chicago (IL); Hybrid; USD 78,000 - 110,000; Full time

Benefits offered by this job

Medical/dental/vision insurance

401(k)

Paid time off

Job summary

AbbVie Analytical Research & Development (Analytical R&D) seeks an Associate Scientist II to generate precise, reliable data and contribute to degradation pathway and stability understanding of drug substances and products.

In a cross-functional environment, you will collaborate with Pre-Clinical Safety, Process Chemistry, Process Engineering and Quality Assurance to support early phase development of NCEs in both preclinical and clinical programs, while adhering to GMP and GxP standards.

Qualifications

• Bachelor's degree in chemistry or analytical chemistry with typically 3+ years’ experience or Master’s degree or equivalent education.
• Theoretical and practical knowledge in chromatography or spectroscopy.
• Hands-on experience with HPLC including testing, basic troubleshooting, and method optimization.
• Basic knowledge of organic chemistry related to degradation pathways.
• Strong organizational and communication skills with high attention to detail.

Responsibilities

• Independently plan and perform routine tasks and generate precise, reliable results.
• Demonstrate experimental precision and data interpretation.
• Document experimental activities in GMP-compliant fashion using electronic data systems.
• Analyze and critique results, noting deviations.
• Troubleshoot experiments and instrumentation.
• Learn new techniques and apply them to project requirements.
• Demonstrate proficiency in analytical techniques and contribute to innovation.

Skills

HPLC

Chromatography

Analytical Chemistry

Data interpretation

GMP

Education

Bachelor's degree in chemistry

Tools

HPLC instrumentation

LC-MS

Job description

Company Description

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn,Facebook,Instagram,XandYouTube.

Job Description

AbbVie Analytical Research & Development (Analytical R&D) is a global analytical scientific organization responsible for all CMC analytical activities related to the development of AbbVie's pharmaceutical products.Our scope includes AbbVie's diverse pipeline of innovative small molecule medicines and spans from the selection of Discovery candidate molecules to Late Stage Clinical.We are building a world-class team of scientists and leaders who will drive the advancement of industry-leading analytical capabilities and make meaningful contributions to advance AbbVie's pipeline of innovative medicines.Careers in AbbVie Analytical R&D provide unique opportunities to work with global and cross-functional teams to drive exceptional science and innovative product development strategies.We are looking for diverse candidates with strong scientific experience to join the AbbVie Analytical R&D team and can offer exciting and rewarding career opportunities for these candidates.

Position Description:

For the Associate Scientist II position, we are seeking a highly motivated candidate who can independently generate precise, reliable and reproducible data in a timely manner, and can demonstrate experimental precision and strong data interpretation skills. They should possess understanding of core discipline and support early phase development of New Chemical Entities (NCEs) drug substance and drug product in both preclinical and clinical programs. As part of the Synthetic Molecule Analytical R&D Predictive Stability team, this role will help build degradation pathway and stability understanding of small molecules, peptides, and other synthetic modalities for new drug substances and drug products. Collaborate within the global Analytical R&D organization and with R&D cross-functional partners such as Pre-Clinical Safety (PCS), Process Chemistry, Process Engineering, Drug Product Development (DPD), and Quality Assurance (QA) and CMC-Regulatory.

Responsibilities:

• Independently plan and perform routine tasks competently within a timely fashion and generate precise, reliable and consistent results.
• Demonstrate experimental precision and strong data interpretation skills and should possess understanding of core discipline.
• Documentation of experimental activities and results in a GMP compliant fashion using an electronic data acquisition and management systems.
• Analyze and critique results, noting significant deviations from the expected results.
• Troubleshoot experiments and instrumentation.
• Learn and understand new experimental techniques with a curiosity to apply them for unique project / assignment requirements.
• Demonstrate skill in multiple techniques and appropriately modify protocols, as required, to suit the changing needs of research or development sciences.
• Place data in proper scientific context by consulting and citing relevant literature.
• Demonstrate technical proficiency in their field, preferentially in the analytical areas of quantitative and instrumental analysis.
• Raises the bar and is never satisfied with the status quo.
• Impact projects predominantly through lab and/or pilot plant based activities.
• Understand and adhere to corporate standards regarding code of conduct, safety, appropriate handling of materials, controlled drug and radioactive compounds, and GxP compliance, where applicable.

Qualifications

• Bachelor’s degree in chemistry, Analytical Chemistry, or equivalent education, with typically 3 or more years’ experience or Master’s Degree or equivalent education (no additional experience).
• Theoretical and practical knowledge (in chromatography and / or spectroscopy is highly preferred) to carry out job function.
• Hands-on experience with HPLC including testing, basic troubleshooting, and method optimization
• Basic knowledge of organic chemistry as related to understanding of possible degradation pathways
• Strong organizational and communication skills with high attention to detail
• Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance.
• Learns fast, grasps the "essence" and can change course quickly where indicated.
• Creates a learning environment, open to suggestions and experimentation for improvement.
• Embraces the ideas of others, nurtures innovation, and manages innovation to reality.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law:

• The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at thetimeofthis posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographiclocation,andwemayultimatelypaymore or less than the posted range. This range may bemodifiedin thefuture.
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.
• This job is eligible toparticipatein our short-term incentiveprograms.

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.Theamountandavailabilityof anybonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employeeremainsin the Company'ssoleandabsolutediscretion unless and until paid andmay bemodifiedat the Company’s sole and absolute discretion, consistent withapplicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

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https://www.abbvie.com/join-us/reasonable-accommodations.html