Associate Scientist I, Genomics & Single-Cell Tech

GenomeWeb; New York, Northern (NY, KY); Hybrid; USD 57,000 - 67,000; Full time

Job summary

The New York Genome Center (NYGC) is seeking an Associate Scientist I in the Technology Development Lab to develop and deploy state-of-the-art genomics techniques. You will join an expert team and collaborate across internal and external groups while advancing single-cell and spatial methodologies in a fast-paced environment.

The role requires a Bachelor’s degree in a relevant field and 2+ years in a molecular biology lab, with sequencing experience preferred.

Qualifications

• Bachelors’ degree in Molecular Biology, Biotechnology, Biochemistry, or related field required.
• 2 years of experience in a molecular biology lab with at least 1+ years of demonstrated experience with next-generation sequencing library prep protocols and sequencing preferred.
• Experience handling RNA and DNA, including extraction, quantification, visualization, modification, hybridization, and PCR is strongly preferred.
• Solid knowledge of molecular biology equipment and related protocols (including RNA and DNA preparation, RNA and DNA quantification, hybridization, PCR, and bead-based solutions) highly preferred.
• Experience with modern molecular biology tools including prior experience working with single-cell suspensions and/or tissue samples, such as cell sorting, nuclei isolation, tissue sectioning, staining, or imaging is a plus.
• Experience working with single cell-based assays or spatial biology platforms is a plus.
• Excellent laboratory and organizational skills including the ability to work independently and efficiently are essential.
• Ability to multitask is a must, along with an orientation toward teamwork and cooperation.
• Strong problem solving, excellent communication, and accurate bench skills required in addition to a passion for learning new things.

Responsibilities

• Carry out procedures associated with DNA and RNA sequencing, including sample QC, library preparation and quantification.
• Assist in performing assays on tissue and/or cell/nuclei suspensions using single cell and spatial methods, including snRNA-Seq, snMultiome, ASAP-Seq, DLP+, Visium HD, Xenium, etc.
• Contribute to the evaluation, development and troubleshooting of new and established methods by performing experiments and other tasks with guidance and supervision.
• Ensure up-to-date standard operating procedures and edit as needed.
• Collaborate closely with colleagues in the Technology Development and Production Lab teams, facilitating knowledge transfer and cross-functional coordination.
• Maintain detailed, reliable, and timely laboratory records - tracking all work and issues in the appropriate databases/tracking sheets and/or electronic lab notebook.
• Assist with regular maintenance of laboratory equipment and actively maintain laboratory cleanliness, organization, and safety procedures.

Skills

Molecular biology

NGS library prep

Single-cell technologies

Spatial biology

Cell/nuclei suspension handling

Laboratory teamwork

Data organization

Interdisciplinary collaboration

Education

Bachelor's degree in Molecular Biology, Biotechnology, Biochemistry, or related field

Tools

Next-generation sequencing instruments

qPCR

Flow cytometer / cell sorter

Job description

The New York Genome Center (NYGC) is seeking an Associate Scientist I in the Technology Development Lab to develop and deploy state-of-the-art genomics techniques. You will join an expert team and collaborate across internal and external groups while advancing single-cell and spatial methodologies in a fast-paced environment.

The role requires a Bachelor’s degree in a relevant field and 2+ years in a molecular biology lab, with sequencing experience preferred.