Associate Scientist, Formulation Development

Eurofins PSS Insourcing Solutions; New London (CT); On-site; USD 75,000 - 110,000; Full time

Benefits offered by this job

Medical coverage

Dental and vision options

Life and disability insurance

401(k) with company match

Paid vacation and holidays

Job summary

Eurofins USA PSS Insourcing Solutions is seeking a formulation specialist to prepare prototypes and develop multiple dosage forms for feasibility studies and small-scale manufacturing. You will measure key properties, assess stability, and identify issues using in-vitro tests to support preclinical and clinical sites.

The role requires experience in amorphous dispersions, modified release designs, and practical chemistry lab skills, with strong data recording and teamwork abilities.

Qualifications

• Experience with drug formulation and pre-formulation techniques.
• Experience with amorphous solid dispersions (spray dried dispersions or hot melt extrusion) and modified release tablet design.
• Basic chemistry (wet or solid state) laboratory experience.
• Experience working with laboratory equipment, mechanically inclined.
• Experience with more advanced characterization techniques such as Raman, thermal analysis and dissolution.
• Ability to follow procedures reliably and consistently,
• Strong computer and organizational skills; Adept in Microsoft Office.
• Excellent communication (oral and written) and attention to detail.
• Ability to learn new techniques, keep accurate records, follow instructions, and comply with company policies.

Responsibilities

• Preparation of prototype formulations for exploratory studies in in-vitro and in-vivo models.
• Development of oral, topical and intravenous (sterile) dosage forms for feasibility studies and small scale manufacturing operations.
• Measurement of key active compound and formulation properties (such as solubility, tablet hardness, disintegration, pH, isotonicity, color, gelling tendency, etc.).
• Assessment of the chemical and physical stability of prototype formulations, as well as the performance of prototype formulations using in-vitro tests (non-sink dissolution, precipitation, etc.).
• Identify potential stability and performance issues with prototype formulations.
• Development of protocols for preparation of formulations at preclinical and clinical study sites.

Skills

Drug formulation

Pre-formulation

Amorphous dispersions

Modified release

Chemistry lab

Raman analysis

Thermal analysis

Dissolution testing

Attention to detail

Job description

Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins laboratories work with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate.

The Eurofins network of companies is the global leader in food, environment, pharmaceutical and cosmetic product testing and in agroscience Contract Research Organisation services. It is one of the market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, advanced material sciences and in the support of clinical studies, as well as having an emerging global presence in Contract Development and Manufacturing Organisations. It also has a rapidly developing presence in highly specialised and molecular clinical diagnostic testing and in-vitro diagnostic products.

In over 30 years, Eurofins has grown from one laboratory in Nantes, France to 58,000 staff across a decentralised and entrepreneurial network of 900 laboratories in over 54 countries. Eurofins companies offer a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products.

In 2021, Eurofins generated total revenues of EUR 6.72 billion, and has been among the best performing stocks in Europe over the past 20 years.

Job Description

• Preparation of prototype formulations (solutions, suspensions, tablets, capsules, powder blends, semi-solid dosage forms, sterile and non-sterile liquids) for exploratory studies in in-vitro and in-vivo models
• Development of oral, topical and intravenous (sterile) dosage forms for feasibility studies and small scale manufacturing operations
• Measurement of key active compound and formulation properties (such as solubility, tablet hardness, disintegration, pH, isotonicity, color, gelling tendency, etc.)
• Assessment of the chemical and physical stability of prototype formulations, as well as the performance of prototype formulations using in-vitro tests (non-sink dissolution, precipitation, etc.)
• Identify potential stability and performance issues with prototype formulations
• Development of protocols for preparation of formulations at preclinical and clinical study sites

Qualifications

• Experience with drug formulation and pre-formulation techniques, and an understanding of drug candidate properties
• Experience with amorphous solid dispersions (spray dried dispersions or hot melt extrusion) and modified release tablet design.
• Basic chemistry (wet or solid state) laboratory experience.
• Experience working with laboratory equipment, mechanically inclined.
• Experience with more advanced characterization techniques such as Raman, thermal analysis and dissolution.
• Ability to follow procedures reliably and consistently,
• Strong computer and organizational skills
• Adept in Microsoft office
• Mathematical or Mechanistic Modeling
• Excellent communication (oral and written) and attention to detail
• Ability to work independently and as part of a team, self-motivated, adaptable, and a positive attitude
• Ability to learn new techniques, keep accurate records, follow instructions, and comply with company policies

Additional Information

• The position is full-time, Monday through Friday, 8am-5 pm
• May be requested to work on weekends, overtime, and holidays based on business needs.
• Candidates currently living within a commutable distance of Groton, CT are encouraged to apply.
• Ability to work overtime as required.
• Excellent full-time benefits, including comprehensive medical coverage, dental, and vision options
• Life and disability insurance
• 401(k) with company match
• Paid vacation and holidays

Eurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer.