Associate Scientist Formulation Development

Eurofins USA PSS Insourcing Solutions; Groton (CT); On-site; USD 28,000 - 40,000; Full time

Benefits offered by this job

Medical, dental, and vision benefits

Life insurance

Disability insurance

401(k) with company match

Paid vacation and holidays

Job summary

Eurofins USA PSS Insourcing Solutions in Groton, CT seeks a formulation specialist to prepare prototype formulations for exploratory studies, covering oral, topical and IV dosage forms for feasibility and small-batch manufacturing. You will measure key properties, assess stability, and run in-vitro tests to evaluate performance of prototypes.

The ideal candidate brings experience with drug formulation, amorphous solid dispersions, and modern analytical techniques, plus strong documentation and

Qualifications

• Experience with drug formulation and pre-formulation techniques.
• Background in amorphous solid dispersions and modified release tablet design.
• Basic chemistry laboratory experience.
• Experience with laboratory equipment and manual dexterity.
• Familiarity with Raman, thermal analysis and dissolution methods.
• Ability to follow procedures reliably and maintain records.
• Strong computer and organizational skills; proficient in MS Office.
• Excellent communication and attention to detail.

Responsibilities

• Prepare prototype formulations for exploratory studies across dosage forms.
• Develop oral, topical and intravenous dosage forms for feasibility studies.
• Measure key properties (solubility, hardness, pH, etc.) of formulations.
• Assess stability and performance via in-vitro tests and non-sink dissolution.
• Identify potential stability issues and develop preclinical protocols.

Skills

Drug formulation

Amorphous solid dispersions

Pre-formulation

Tablet design

Dissolution testing

Analytical techniques

Communication skills

Independent worker

Team collaboration

Lab techniques

Education

Chemistry background

Laboratory experience

Wet chemistry

Tools

Raman spectroscopy

Thermal analysis

Dissolution apparatus

Spray drying

Hot melt extrusion

Job description

Job Description

• Preparation of prototype formulations (solutions, suspensions, tablets, capsules, powder blends, semi-solid dosage forms, sterile and non-sterile liquids) for exploratory studies in in-vitro and in-vivo models
• Development of oral, topical and intravenous (sterile) dosage forms for feasibility studies and small scale manufacturing operations
• Measurement of key active compound and formulation properties (such as solubility, tablet hardness, disintegration, pH, isotonicity, color, gelling tendency, etc.)
• Assessment of the chemical and physical stability of prototype formulations, as well as the performance of prototype formulations using in-vitro tests (non-sink dissolution, precipitation, etc.)
• Identify potential stability and performance issues with prototype formulations
• Development of protocols for preparation of formulations at preclinical and clinical study sites

Qualifications

_ The Ideal Candidate would possess:_

• Experience with drug formulation and pre-formulation techniques, and an understanding of drug candidate properties
• Experience with amorphous solid dispersions (spray dried dispersions or hot melt extrusion) and modified release tablet design.
• Basic chemistry (wet or solid state) laboratory experience.
• Experience working with laboratory equipment, mechanically inclined.
• Experience with more advanced characterization techniques such as Raman, thermal analysis and dissolution.
• Ability to follow procedures reliably and consistently,
• Strong computer and organizational skills
• Adept in Microsoft office
• Mathematical or Mechanistic Modeling
• Excellent communication (oral and written) and attention to detail
• Ability to work independently and as part of a team, self-motivated, adaptable, and a positive attitude
• Ability to learn new techniques, keep accurate records, follow instructions, and comply with company policies

Additional Information

• The position is full-time, Monday through Friday, 8am-5 pm
• May be requested to work on weekends, overtime, and holidays based on business needs.
• Ability to work overtime as required.
• Excellent full-time benefits, including comprehensive medical coverage, dental, and vision options
• Life and disability insurance
• 401(k) with company match
• Paid vacation and holidays

Eurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer.

Compensation:
$25-$25