Associate Scientist, Early Preclinical Development - Inner Ear Biology

Eli Lilly; Honolulu (HI); On-site; USD 70,000 - 100,000; Full time

Job summary

Eli Lilly and Company in Honolulu, Hawaii seeks an Associate Scientist with inner ear histology expertise to support discovery and IND-enabling animal studies.

The ideal candidate will perform micrdissections of mouse and NHP inner ear tissues, process samples for embedding and frozen sections, and prepare tissues for molecular analyses, IHC, and imaging. Collaborative, fast-paced environment with data presentation responsibilities.

Qualifications

• Bachelor's degree with 0+ years of experience, or high school diploma with 2+ years hands-on inner ear biology experience.
• Experience with inner ear dissection, tissue preparation, embedding and sectioning.
• Experience with immunohistochemistry and imaging techniques.
• Knowledge of cochlear anatomy and microdissection methods.

Responsibilities

• Perform mouse and NHP inner ear microdissections
• Perform NHP temporal bone extraction and processing
• Prepare inner ear tissues for embedding and preparation for frozen sections
• Preparation of inner ear tissues for molecular analyses
• Perform immunohistochemistry
• Perform epifluorescent imaging, cochlear frequency mapping, and confocal microscopy
• Produce graphs and charts from histologic data
• Preparation of histologic images for presentation
• Development and/or review of immunohistochemistry protocols
• Inventory ordering and database management
• Collaborate closely with cross-functional teams and external groups to coordinate and drive complex studies
• Weekend work may be required at times

Skills

Python

MATLAB

Image analysis

Histology

Cochlear anatomy

IHC

Education

Bachelor's Degree

High School Diploma

Tools

ImageJ

Amira

LasX

Imaris

Excel

PowerPoint

Word

Adobe Suite

Job description

Job Overview

The Early Preclinical Development (EPD) Team is seeking an Associate Scientist with experience in inner ear histology to support discovery and IND‑enabling animal studies.

The ideal candidate will have experience in histologic techniques specific to the inner ear, such as microdissection of the mouse and non‑human primate (NHP) inner ear tissues into discrete anatomical regions, and further processing of these tissues using various histologic techniques, in addition to imaging, analysis, and preparation of data for presentation. Cross‑functional work may be required to advance company goals. The successful candidate will be self‑motivated and creative, with a desire to succeed at the highest level in a highly collaborative and fast‑paced environment.

Job Responsibilities

• Perform mouse and NHP inner ear microdissections
• Perform NHP temporal bone extraction and processing
• Prepare inner ear tissues for embedding and preparation for frozen sections
• Preparation of inner ear tissues for molecular analyses
• Perform immunohistochemistry
• Perform epifluorescent imaging, cochlear frequency mapping, and confocal microscopy
• Produce graphs and charts from histologic data
• Preparation of histologic images for presentation
• Development and/or review of immunohistochemistry protocols
• Inventory ordering and database management
• Collaborate closely with cross‑functional teams and external groups to coordinate and drive complex studies
• Weekend work may be required at times

Basic Qualifications

• Bachelor's Degree with 0+ years of experience, or high school diploma and 2+ years of hands‑on experience with inner ear biology.

Additional Skills and Preferences

• Experience in solving scientific problems and/or image analysis using programming languages
• Experience and programming skills in at least one language such as Python or MATLAB
• Knowledge of cochlear anatomy, cochlear microdissection (whole‑mount and sections), and methods for histological preparation of inner ear tissues required
• Experience with modern imaging techniques; epifluorescent and confocal microscopy required
• Excellent computer skills; proficiency in Microsoft Office (Word, Excel, Teams, PowerPoint, Outlook, Adobe Suite)
• Experience with image analysis software (ImageJ, Amira, LasX, Imaris); may include coding
• Excellent laboratory technical lab skills (pipetting, reagent preparation, liquid handling)

Accommodations

Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively “Lilly”) are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs.

If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ([e-mail]) for further assistance. Please note this email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.

EEO Statement

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.