Biologist – Neurodegeneration, Histology/Imaging

BioSpace; Indianapolis (IN); On-site; USD 65,250 - 169,400; Full time

Benefits offered by this job

401(k)

Pension

Vacation

Medical benefits

Dental benefits

Vision benefits

Life insurance

Job summary

A global healthcare leader in Indianapolis is seeking a motivated scientist to join their Neurodegeneration team. The candidate will utilize advanced histological and imaging techniques to support therapeutic investigations for neurodegenerative diseases. Responsibilities include performing histological lab techniques, conducting experiments, and analyzing data. The ideal applicant holds a BS in Neuroscience or related fields with at least 2 years of experience. Competitive compensation and comprehensive benefits are offered.

Qualifications

• Two years of experience with histologic analysis of animal models.
• Ability to work in a fast-paced environment.
• Strong organization skills and attention to detail.

Responsibilities

• Perform histological lab techniques including tissue processing and imaging.
• Establish and execute multiplexed immunohistochemistry.
• Assist in troubleshooting and data analysis.

Skills

Histological lab techniques

Immunohistochemistry

Data analysis

Communication skills

Experiment design

Education

BS in Neuroscience or related fields

Tools

Imaging software (HALO, QuPath, ImageJ)

Autostainer (Leica Bond-RX)

Slide scanner (Olympus VS200)

Job description

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 39,000 employees worldwide work to discover and bring life‑changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Organization Overview

We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 39,000 employees around the world work, discover and bring life‑changing medicines, improve understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We put people first and seek individuals determined to make life better for people worldwide.

Responsibilities

Eli Lilly and Company seeks a highly motivated scientist to join our Neurodegeneration team. This position is part of a multidisciplinary team dedicated to discovering novel medicines for the treatment of Alzheimer’s disease, Parkinson’s disease, ALS, and other related neurodegenerative conditions. The individual will apply cutting‑edge histological and imaging techniques to support our expanding neurodegeneration portfolio. A primary focus of this position will be the establishment and utilization of imaging/histological techniques to support therapeutic investigations in multiple pre‑clinical animal models.

Key Objectives/Deliverables

• Perform histological lab techniques including tissue processing, paraffin embedding, tissue sectioning, routine and special tissue staining, imaging, and image analysis.
• Establish and execute multiplexed immunohistochemistry (IHC) and in situ hybridization (RNAScope) to evaluate in‑vivo efficacy of therapeutic agents.
• Contribute to development, validation, and performing advanced histological/imaging techniques like spatial transcriptomics, super‑resolution microscopy, light‑sheet microscopy, and in‑vivo two‑photon imaging.
• Assist in troubleshooting technical challenges and provide scientific/technical input to project teams.
• Design, execute experiments, and perform data analysis.
• Communicate results to the project team to drive data‑driven decisions.
• Provide written and verbal communication of work in lab reports and team meetings.
• Accurately record all practical work: completion of electronic notebooks to Lilly procedure quality standards.
• Perform general laboratory assistance, including ordering and receiving lab supplies, preparation of reagents, and maintaining laboratory equipment.
• Ensure compliance with all health and safety regulations.
• Report on‑site, in the lab, five days a week.

Basic Requirements

• BS in Neuroscience, biological sciences, or related fields.
• Two years of academic or industry experience with histologic analysis of animal models.

Additional Skills / Preferences

• Previous experience in neuroscience research.
• Hands‑on experience in autostainer (e.g., Leica Bond‑RX) and slide scanner imaging (e.g., Olympus VS200).
• Knowledge of image‑analysis software packages: HALO, QuPath, and ImageJ.
• Experience in stereotactic surgery and in‑vivo imaging.
• Hands‑on experience in cDNA library preparation for transcriptomics.
• Ability to design, execute, and interpret experiments independently.
• Excellent communication skills and efficiency in collaborating across functional teams.
• Strong organization skills, attention to detail, critical thinking, multitasking, and a desire to learn new techniques and contribute to cutting‑edge projects in a fast‑paced working environment.

Additional Information

Eli Lilly and Company, Lilly USA, LLC, and our wholly owned subsidiaries are committed to helping individuals with disabilities participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation, please email Lilly Human Resources ([e-mail]) for further assistance. Lilly is an Equal Opportunity/affirmative action employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability, or any other legally protected status. Compensation ranges from $65,250 to $169,400 and is determined by education, experience, skills, and geographic location. Eligible full‑time employees are also eligible for a company bonus and a comprehensive benefit program that includes 401(k), pension, vacation, medical, dental, vision, prescription drug, flexible spending account, life insurance, leave, and well‑being benefits. #WeAreLilly