Associate Scientist, Cancer Genomics & CRISPR

St. Jude Children's Research Hospital, Inc.; Memphis (TN); On-site; USD 86,000 - 155,000; Full time

Job summary

St. Jude Children's Research Hospital in Memphis seeks an Associate Scientist or Scientist to join Dr. Christopher Vakoc's laboratory, advancing cancer gene regulation and functional genomics for childhood cancers with translational impact.

The role emphasizes CRISPR-based screening, genome-scale analyses, and collaboration across bench-to-bedside projects using mouse and zebrafish models and in vivo systems.

Qualifications

• Background in molecular biology with DNA/RNA/protein analysis experience.
• Experience with mammalian cell culture and cellular assays.
• Proficiency in gene editing and functional genomics techniques.
• Experience using in vivo mouse and/or zebrafish models.

Responsibilities

• Conduct and support research projects using molecular biology, cell biology, and genomics techniques.
• Perform experiments involving DNA, RNA, and protein analysis, mammalian cell culture, molecular cloning, lentiviral systems, and CRISPR-based technologies.
• Utilize mouse and/or zebrafish models to investigate gene function, disease mechanisms, and cellular pathways.
• Design, optimize, and execute research protocols; analyze, interpret, and summarize experimental data.
• Contribute to scientific presentations, reports, and manuscript preparation.
• Maintain laboratory operations, including equipment maintenance, troubleshooting, inventory management, and supply ordering.
• Train and support laboratory personnel in standard techniques and procedures.
• Perform other duties as assigned to support departmental and institutional research goals.

Skills

Molecular biology

Mammalian cell culture

Molecular cloning

Lentiviral design

CRISPR-based technologies

In vivo mouse models

Zebrafish models

Education

Bachelor's degree in a relevant scientific field

Master’s degree with 6+ years of experience

PhD with 3+ years of experience

Tools

Lentiviral systems

CRISPR technologies

Mouse models

Zebrafish models

Job description

St. Jude Children's Research Hospital in Memphis seeks an Associate Scientist or Scientist to join Dr. Christopher Vakoc's laboratory, advancing cancer gene regulation and functional genomics for childhood cancers with translational impact.

The role emphasizes CRISPR-based screening, genome-scale analyses, and collaboration across bench-to-bedside projects using mouse and zebrafish models and in vivo systems.