Associate Scientist

Secant-Group,-LLC

Telford (PA)

On-site

USD 65,000 - 90,000

Full time

3 days ago
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Job summary

Secant Group is seeking an Associate Scientist in Telford, PA to support formulation development and characterization of polymeric materials for biomedical implants and drug-delivery devices.

You will conduct pre-formulation studies, perform particle size analysis and microscopy, and use DSC, TGA, rheometry, FTIR, Raman, and HPLC to evaluate drug-polymer interactions and release profiles. Collaboration with R&D is essential.

Qualifications

  • Laboratory-based formulation and characterization experience with polymeric materials.
  • Experience with pre-formulation studies and analytical techniques.

Responsibilities

  • Formulate and characterize polymeric materials for drug-eluting and non-drug-eluting implantable devices.
  • Execute pre-formulation studies including particle size analysis, SEM, light microscopy, milling, and sieving.
  • Characterize polymers and drug-polymer interactions using DSC, TGA, and rheometry.
  • Analyze formulations with FTIR and Raman spectroscopy for drug-polymer mixing, loading, and uniformity.
  • Set up and run dissolution studies to determine drug release profiles using HPLC for quantification.
  • Conduct degradation studies by measuring weight, dimensions and topography to assess polymer degradation.
  • Perform wet chemistry experiments including residual monomer extractions, Karl Fischer titrations, and acid/base titrations.
  • Collaborate with R&D teammates to achieve project goals.

Tools

DSC
TGA
Rheometry
FTIR
Raman spectroscopy
HPLC
Dissolution testing
Degradation analysis

Job description

Secant Group - Telford, PA
Telford, PA 18969, USA

  • On-site
  • Research
  • Full-Time
  • Requisition #: ASSOC002586
Description

What we are looking for:

The Associate Scientist position is a laboratory-based scientific role in a fast-paced, multidisciplinary team environment. In this role, you will be supporting product formulation development and characterization focused on biomedical implants and pharmaceutical devices for controlled drug delivery utilizing Secant Group’s biomaterial platform.

What you will do:

  • Formulate and characterize polymeric materials designed for drug-eluting and non-drug-eluting implantable devices to support customer projects and internal investigations.
  • Execute pre-formulation studies, such as drug particle size analysis, SEM, light microscopy, milling, and sieving.
  • Characterize polymers and drug-polymer physiochemical interactions using DSC, TGA, rheometry.
  • Analyze formulations using FTIR and Raman spectroscopy to determine drug-polymer mixing efficiency, drug loading, and content uniformity.
  • Set up and run dissolution studies and analyze dissolution media to determine drug release profiles using HPLC to quantify drug concentration.
  • Set up and run degradation studies and analyze sample weight, dimensions, and topography to determine polymer degradation behavior.
  • Perform wet chemistry experiments, like residual monomer extractions, Karl Fischer titrations, and acid/base titrations.
  • Collaborate with other teammates within R&D to achieve project goals.

Who you are:

  • Formulate and characterize polymeric materials designed for drug-eluting and non-drug-eluting implantable devices to support customer projects and internal investigations.
  • Execute pre-formulation studies, such as drug particle size analysis, SEM, light microscopy, milling, and sieving.
  • Characterize polymers and drug-polymer physiochemical interactions using DSC, TGA, rheometry.
  • Analyze formulations using FTIR and Raman spectroscopy to determine drug-polymer mixing efficiency, drug loading, and content uniformity.
  • Set up and run dissolution studies and analyze dissolution media to determine drug release profiles using HPLC to quantify drug concentration.
  • Set up and run degradation studies and analyze sample weight, dimensions, and topography to determine polymer degradation behavior.
  • Perform wet chemistry experiments, like residual monomer extractions, Karl Fischer titrations, and acid/base titrations.
  • Collaborate with other teammates within R&D to achieve project goals.

Equal Opportunity Employer/Protected Veterans/Individuals with Disabilities
This employer is required to notify all applicants of their rights pursuant to federal employment laws.For further information, please review the Know Your Rights notice from the Department of Labor.

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